Vision Research Grants (Assistance Listing 93.867)

National Institutes of Health · Amount varies

This NIH HEAL Initiative UG3/UH3 cooperative agreement funds preclinical optimization and development of safe, non-addictive small-molecule and biologic therapeutics for treating pain, advancing candidates toward Phase II trials. Applicants must already have a promising lead candidate, a strong biological rationale, and established assays. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH Predoctoral-to-Postdoctoral Transition Award (F99/K00) supports promising graduate students as they finish doctoral research and move into mentored postdoctoral career development, in NIH mission-relevant fields. It is a mentored training award administered through institutions; candidates may not lead an independent clinical trial but may participate in a sponsor-led one. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Up to $375K

This NIH R15 (REAP) award funds small-scale research and student research experiences at health-professional and graduate schools that receive limited NIH funding, with a minimal-risk clinical trial required. Eligibility is restricted to degree-granting institutions that have received no more than $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. Awards reach up to about $375,000. The NIH-funding cap and institution-type limits make eligibility narrow, so verify your institution qualifies.

National Institutes of Health · Amount varies

This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative U01 funds development of scalable technologies to map brain connectivity across scales in humans, non-human primates, and mice, feeding into the BRAIN CONNECTS network; no clinical trial is allowed. Eligibility is described in the funding notice, and foreign organizations and their U.S. components may apply. No award amount is specified. Funded projects must integrate into a coordinated network, so review the notice's eligibility details carefully.

National Institutes of Health · Amount varies

This NIH SBIR Phase IIB award is restricted to U.S. small business concerns that have previously received an NIH SBIR or STTR Phase II award; it bridges the gap between Phase II and commercialization for later-stage R&D. Only one such award is allowed per project, and applications must be submitted within the first six due dates after the Phase II budget period ends, so it is narrow and limited to existing grantees. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH SBIR/STTR Commercialization Readiness Pilot (CRP) is restricted to U.S. small business concerns (as defined by the SBA) and helps move NIH-funded SBIR/STTR projects from late-stage development toward commercialization. It supports later-stage R&D and technical assistance such as replication studies, IND/IDE-enabling work, clinical studies, manufacturing scale-up, and regulatory support, and a significant portion may be subcontracted. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · $25K–$250K

This NIH S10 instrumentation grant funds resource-limited institutions to purchase state-of-the-art scientific instruments supporting biomedical research and education. It is a limited competition that invites applications only from eligible organizations, and awards range from about $25,000 to $250,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.

National Institutes of Health · Up to $500K

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.

National Institutes of Health · Up to $200K

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R21 funds exploratory, higher-risk Down syndrome research — feasibility studies, novel methods, or new applications of existing techniques. Awards up to about $200,000.

National Institutes of Health · Up to $500K

This NIH (R01) Bioengineering Research Grant funds multidisciplinary projects that apply engineering approaches to biomedical, clinical, or translational problems, with a stated budget up to about $500,000. It supports clinical trials that validate performance but excludes Phase III trials, conventional non-translational trials, and commercial production. Eligibility is relatively broad for an NIH grant: both foreign organizations and foreign components of U.S. organizations are eligible to apply, though foreign components (as defined by NIH) are not allowed.

National Institutes of Health · Up to $700K

An NIH BRAIN Initiative R61 funding exploratory human neuroscience using invasive neural recording and stimulation during surgical procedures. Foreign organizations and foreign components are not eligible; the work requires multidisciplinary teams with access to neurosurgical settings. Awards reach up to about $700,000, and clinical trials are not allowed. This is a highly specialized research award for institutions with relevant clinical/research capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R01 funding discovery and optimization of in vivo chemical probes for novel nervous-system targets, with applicants expected to already have validated starting compounds and bioassays in hand. Domestic and foreign organizations and foreign components are eligible to apply. No award amount is specified, and clinical trials are not allowed. This is a research grant for investigators with existing medicinal-chemistry capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative R01 funds development of computational theories, models, and methods for analyzing complex brain-circuit data, to be shared with the research community. Eligible applicants are research organizations, including faith- or community-based organizations, tribal governments, foreign organizations, and U.S. territories; it targets institutions rather than individuals. No award amount is specified. The work is narrowly scoped to neural-circuit tool building, so confirm fit before applying.

National Institutes of Health · Amount varies

An NIH (R38) award supporting in-depth research experiences for resident clinicians early in their careers to build a pipeline of clinician-investigators. Eligible applicants are domestic institutions and organizations such as universities, tribal governments, and faith- or community-based organizations; foreign organizations and foreign components are not eligible. No award amount is stated. This is a structured research-training mechanism aimed at academic and clinical institutions rather than individuals applying directly.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government and tribal organizations; foreign organizations are not eligible. This NIH R21 funds exploratory, early-stage projects developing methods or agents to target 'undruggable' molecules in serious diseases. Award size isn't specified and follows standard NIH R21 limits; best suited to researchers pursuing high-risk, innovative therapeutics.

National Institutes of Health · Amount varies

This NIH program (Blueprint MedTech Translator) funds translational research and clinical feasibility studies for therapeutic and diagnostic devices targeting nervous- or neuromuscular-system disorders, open to a broad range of institutions including HBCUs, Hispanic-serving institutions, tribal colleges, faith- and community-based organizations, and individuals or businesses developing their own devices. It is a milestone-driven cooperative agreement requiring NIH staff involvement in project planning and monitoring. No award amount is specified, and the deadline is not imminent.

National Institutes of Health · Up to $100K

This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.

National Institutes of Health · Up to $125K

This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students in combined MD/PhD or similar dual-doctoral degree programs at institutions that already have an NIH-funded dual-degree training program, preparing them for physician-scientist careers. It is limited to individual student applicants; foreign organizations and their non-U.S. components are not eligible, and applicants may not lead an independent clinical trial. No award amount is listed, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual predoctoral students conducting dissertation research in health-related fields under a faculty sponsor, with the goal of developing them into independent researchers. It is limited to individual applicants (not organizations); foreign organizations are named as an other-eligible category, and applicants may not lead an independent clinical trial. No specific award amount is listed, and the deadline is several years out.

National Institutes of Health · Amount varies

This NIH R01 grant funds research applications studying the ethical, legal, and social implications of human genetics and genomics, using empirical, conceptual, legal, or normative methods. Applications must include a Plan for Enhancing Diverse Perspectives (PEDP); those without one won't be reviewed. It's aimed at eligible U.S. and territorial research institutions, and the deadline is November 18, 2026.

National Institutes of Health · Amount varies

This NIH R21 grant funds exploratory and developmental research into the ethical, legal, and social implications of human genetics and genomics, particularly studies examining new or emerging genomic technologies. It's open to eligible U.S. and territorial research institutions using empirical, conceptual, legal, or normative methods. The deadline is November 18, 2026.

National Institutes of Health · Up to $150K

An NIH/NEI planning grant (R34, clinical trial not allowed) supporting development of study protocols and manuals of procedures for future clinical vision research, including trials and epidemiologic studies. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $150,000. Funds cannot be used to generate intervention-effect data, so this is a planning mechanism for research institutions.

National Institutes of Health · Amount varies

Open to domestic institutions — universities, research institutions, nonprofits, and certain government/tribal organizations (foreign institutions are not eligible). This NIH T35 funds short-term (often summer) research-training experiences for health-professional and graduate students. It supports the institution's training program rather than an individual.

National Institutes of Health · Amount varies

This NIH/NEI R21 funds vision-related research projects based on secondary analysis of existing datasets, including related statistical methodology development; no clinical trial is allowed. Eligible applicants are research and education institutions, including minority-serving and tribal-serving institutions, faith- or community-based organizations, and tribal governments; it targets research organizations rather than individuals. No award amount is specified. The focus is limited to vision-related secondary data analysis.

National Institutes of Health · Up to $499K

An NIH/NCI research project grant (R01, clinical trial not allowed) funding academic-industrial partnerships to translate scientific and engineering advances into tools for disease risk assessment, detection, diagnosis, and treatment. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $499,000. The partnership focus suits research institutions collaborating with industry rather than individuals.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial required) supports early-stage research projects with at least one clinical trial, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Up to $375K

The REAP program funds small-scale research at health professional and graduate schools that haven't been major recipients of NIH support, while giving students hands-on research experience. Eligibility is limited to institutions awarding NIH-relevant degrees that received under $6 million per year in NIH support in 4 of the last 7 years — a specific financial threshold worth checking before applying. Awards go up to $375,000.

National Institutes of Health · Up to $375K

An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.

National Institutes of Health · Amount varies

This NIH AREA (R15) award funds small-scale research at undergraduate-focused institutions that receive limited NIH funding, emphasizing undergraduate research experiences; a minimal-risk clinical trial is required. Eligible institutions must grant baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.

National Institutes of Health · Amount varies

An NIH BRAIN Initiative R01 funding the development and validation of novel tools to study cell-type- and circuit-specific processes in the brain. Eligibility is geared toward research institutions, including HBCUs, Hispanic-serving and Tribal colleges, and foreign organizations; this is a federal research grant, not a fit for typical nonprofits, small businesses, or individuals without an academic/research affiliation. No award amount is specified. Clinical trials are not allowed under this opportunity.

National Institutes of Health · Amount varies

This NIH (U01) program funds academic-industry research partnerships that develop and advance bioengineering tools and technologies to address biomedical problems, aiming for solutions deployable within roughly 5-10 years. Eligible applicants are research organizations including universities, colleges, government and tribal entities, and faith- or community-based organizations; it is geared toward multidisciplinary research teams partnered with industry, not individuals or general nonprofits. Award amounts are not specified. Applicants should expect a collaborative, milestone-driven structure.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative program (UG3/UH3) is a milestone-driven cooperative agreement supporting translational development and small clinical studies of next-generation therapeutic and diagnostic devices for nervous and neuromuscular disorders. Eligible applicants are institutions, including minority-serving institutions, HBCUs, and tribal colleges; foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components are otherwise allowed. NIH program staff participate in project planning and monitoring. No award amount is stated; eligibility centers on research institutions able to develop and test devices.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative program (UH3) funds small clinical trials to advance next-generation devices for recording and modulating the human central nervous system. Eligible applicants are institutions, including minority-serving institutions, HBCUs, and tribal colleges; foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components are otherwise allowed. No award amount is stated. This is a clinical-research mechanism aimed at research institutions capable of conducting device trials.

National Institutes of Health · Up to $500K

An NIH UC2 program helping resource-limited organizations build biomedical research capacity and sponsored-programs administration. Eligible applicants include minority-serving and Tribal colleges and other domestic organizations with limited research resources; foreign organizations are not eligible. Awards reach up to about $500,000. This targets emerging or under-resourced research institutions rather than general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH R01 funds research identifying and testing strategies to help evidence-based health interventions get adopted, scaled, and sustained — or, conversely, to phase out ineffective practices. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations across NIH's mission areas. No award amount is specified.

National Institutes of Health · Amount varies

This NIH Shared Instrumentation Grant (SIG) program funds groups of NIH-supported investigators to purchase or upgrade a single specialized research instrument, with awards from $50,000 up to $750,000. Eligible applicants are U.S. research institutions, including minority-serving and tribally controlled colleges; foreign organizations and their components are not eligible and foreign components are not allowed. It requires groups of existing NIH-supported investigators, so it is not for individuals, new organizations, or general nonprofits. This is a large-award instrumentation grant for established research institutions.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative (U01) program funds development of next-generation sensors and bioelectronic devices that synchronize with brain recordings to build computational models of human and animal behavior. Eligible applicants are research organizations including universities, colleges, government and tribal entities, and faith- or community-based organizations; it targets established research and technology-development teams, not individuals or general nonprofits. Award amounts are not specified. Confirm program-specific eligibility in the full announcement.

National Institutes of Health · Amount varies

This NIH/Fogarty K43 career development award supports an early-career scientist at an academic or research institution in a low- or middle-income country, for research that does not involve leading an independent clinical trial. Eligibility is narrow and country-restricted: only foreign institutions in qualifying LMICs may apply, U.S. organizations and their foreign components are not eligible, and some upper-middle-income G20 countries are excluded. This is not available to U.S. applicants. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH program supports preclinical discovery and development of biologic-based therapies for nervous system disorders, from lead optimization through Phase I clinical testing. Eligible applicants are research organizations such as universities, colleges, government and tribal agencies, faith- or community-based organizations, and (for this announcement) foreign organizations; it is geared toward established research teams, not individuals or general nonprofits. Award amounts are not specified. Applicants should be prepared for a complex, multi-phase research undertaking with NIH-funded consultants and contract research organizations.

National Institutes of Health · Amount varies

This NIH (R13) program supports conferences and scientific meetings relevant to public health and the missions of participating NIH institutes. Eligible applicants are U.S. research and education organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Note that R13 conference support typically requires advance permission from the funding institute before applying. It is aimed at organizations hosting scientific conferences, not individuals. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative (U24) program funds establishment of facilities at minority-serving institutions and IDeA-eligible institutions to produce and distribute brain cell type-specific research reagents to the neuroscience community. Eligibility is narrowed to minority-serving and IDeA-eligible U.S. institutions; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It is intended for qualifying research institutions, not individuals or general nonprofits, and awardees must coordinate with existing Armamentarium project teams. Award amounts are not specified.

National Institutes of Health · Up to $350K

This NIH HEAL Initiative R61/R33 funds early translational drug-discovery research toward non-addictive pain therapeutics, including assay development, screening, and initial characterization of candidate agents; no clinical trial is allowed. Eligible applicants include universities, research institutions, and tribal and community organizations, but foreign organizations are not eligible to apply. The maximum award is about $350,000. It requires drug-discovery research capacity.

National Institutes of Health · Amount varies

This NIH R50 award provides salary support for established Research Software Engineers who build and disseminate biomedical software, tools, and algorithms. Eligible applicants include universities and research institutions; foreign (non-U.S.) organizations are not eligible to apply. It is tied to an existing research environment and specialized staff, so it suits research institutions rather than general nonprofits or individuals applying on their own. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH research education (R25) grant funds summer research experiences for high school or undergraduate students, or science teachers, tied to a participating institute's mission rather than general STEM. It is aimed at eligible institutions such as universities, nonprofits, and government agencies that would run the program; foreign organizations and foreign components are not allowed and clinical trials are not permitted. No award amount is listed.

National Institutes of Health · Up to $375K

This NIH R15 (AREA) award supports small-scale research at undergraduate-focused institutions that receive limited NIH funding, with a required clinical trial. Eligibility is restricted to institutions that award baccalaureate science degrees and have received no more than $6 million/year of NIH support in 4 of the last 7 years; foreign organizations are not eligible to apply. The maximum award is about $375,000. This is narrowly targeted at less-research-intensive degree-granting institutions.

National Institutes of Health · Amount varies

This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.

National Institutes of Health · Up to $750K

An NIH BRAIN Initiative R18 funding preclinical proof-of-concept work on novel recording and modulation technologies for the human central nervous system, up to readiness for first-in-human studies. The eligibility text is mixed but states foreign organizations and foreign components are not eligible to apply, while domestic research institutions, minority-serving and Tribal colleges may. Awards reach up to about $750,000, and clinical trials are not allowed. This is a specialized research award, not a fit for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

NIH mechanism allowing existing award recipients to apply for revision (supplemental) funding to expand a current NIH grant or cooperative agreement, only in response to a specific Notice of Special Interest. Restricted to organizations that already hold an active NIH single-project award. No award amount is specified. Because applicants must already be NIH grantees and respond to a matching NOSI, eligibility is narrow and not open to new applicants.