Drug Use and Addiction Research Programs Grants (Assistance Listing 93.279)

National Institutes of Health · Amount varies

This NIH HEAL Initiative UG3/UH3 cooperative agreement funds preclinical optimization and development of safe, non-addictive small-molecule and biologic therapeutics for treating pain, advancing candidates toward Phase II trials. Applicants must already have a promising lead candidate, a strong biological rationale, and established assays. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH Predoctoral-to-Postdoctoral Transition Award (F99/K00) supports promising graduate students as they finish doctoral research and move into mentored postdoctoral career development, in NIH mission-relevant fields. It is a mentored training award administered through institutions; candidates may not lead an independent clinical trial but may participate in a sponsor-led one. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Amount varies

This NIH (R03) award helps investigators enter high-priority substance use research, including HIV comorbidity, by funding the collection of preliminary data to support future larger grants and career advancement. Eligibility is comparatively open for NIH: foreign organizations and foreign components of U.S. organizations are both eligible to apply, and foreign components are allowed. It suits researchers and institutions transitioning into substance use research fields. No specific award amount is listed.

National Institutes of Health · Amount varies

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH DP1 (Avant-Garde/Avenir) funds high-risk, high-reward research on HIV and substance use — basic, clinical, translational, or implementation science. It backs bold, transformative ideas; award size follows the DP1 mechanism.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH HEAL Initiative R61/R33 grant funds action-oriented research that translates addiction epidemiology, prevention, treatment, and recovery findings into practice to address the opioid crisis and overdose. Projects can target individual, provider, organizational, community, or system levels. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.

National Institutes of Health · Up to $375K

This NIH R15 (REAP) award funds small-scale research and student research experiences at health-professional and graduate schools that receive limited NIH funding, with a minimal-risk clinical trial required. Eligibility is restricted to degree-granting institutions that have received no more than $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. Awards reach up to about $375,000. The NIH-funding cap and institution-type limits make eligibility narrow, so verify your institution qualifies.

National Institutes of Health · Amount varies

This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative U01 funds development of scalable technologies to map brain connectivity across scales in humans, non-human primates, and mice, feeding into the BRAIN CONNECTS network; no clinical trial is allowed. Eligibility is described in the funding notice, and foreign organizations and their U.S. components may apply. No award amount is specified. Funded projects must integrate into a coordinated network, so review the notice's eligibility details carefully.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH U54 cooperative agreement funds establishment of a Center that trains researchers in product development for new substance use disorder (SUD) pharmacotherapeutics and advances promising concepts with technical and financial support. Unusually for NIH, foreign organizations and foreign components are eligible to apply under this opportunity. Clinical trials are not allowed under this mechanism. No specific award amount is stated; refer to the NOFO for full eligibility details.

National Institutes of Health · Amount varies

The NIH Science Education Partnership Award (SEPA, R25) funds educational projects that increase understanding of biomedical research among pre-college (pre-K through grade 12) students and encourage interest in STEM careers. It suits universities, research institutions, and education-focused organizations that can run science education programs. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Up to $300K

This NIH R01 grant funds basic research into how toxic chemicals of concern injure the skin, supporting the development of medical countermeasures for chemical disasters and emergencies. The award ceiling is up to about $300,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.

National Institutes of Health · Up to $700K

An NIH BRAIN Initiative R61 funding exploratory human neuroscience using invasive neural recording and stimulation during surgical procedures. Foreign organizations and foreign components are not eligible; the work requires multidisciplinary teams with access to neurosurgical settings. Awards reach up to about $700,000, and clinical trials are not allowed. This is a highly specialized research award for institutions with relevant clinical/research capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R01 funding discovery and optimization of in vivo chemical probes for novel nervous-system targets, with applicants expected to already have validated starting compounds and bioassays in hand. Domestic and foreign organizations and foreign components are eligible to apply. No award amount is specified, and clinical trials are not allowed. This is a research grant for investigators with existing medicinal-chemistry capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH R01 supports research institutions and investigators studying how to design rigorous clinical trials of rapid-acting psychotropic drugs (RAPIDs) and adjunctive psychosocial interventions. A clinical trial is required, so applicants must be prepared to run one. Foreign (non-U.S.) organizations, foreign components of U.S. organizations, and foreign components generally are not eligible or allowed. The notice does not state an award ceiling; refer to the NOFO for eligibility and budget details.

National Institutes of Health · Amount varies

This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative R01 funds development of computational theories, models, and methods for analyzing complex brain-circuit data, to be shared with the research community. Eligible applicants are research organizations, including faith- or community-based organizations, tribal governments, foreign organizations, and U.S. territories; it targets institutions rather than individuals. No award amount is specified. The work is narrowly scoped to neural-circuit tool building, so confirm fit before applying.

National Institutes of Health · Up to $3M

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH UG3/UH3 funds discovery and development of interventions — medications and devices — to prevent and treat substance use disorders and overdose, including preclinical and clinical studies. Awards up to about $3,000,000.

National Institutes of Health · Amount varies

This NIH program (Blueprint MedTech Translator) funds translational research and clinical feasibility studies for therapeutic and diagnostic devices targeting nervous- or neuromuscular-system disorders, open to a broad range of institutions including HBCUs, Hispanic-serving institutions, tribal colleges, faith- and community-based organizations, and individuals or businesses developing their own devices. It is a milestone-driven cooperative agreement requiring NIH staff involvement in project planning and monitoring. No award amount is specified, and the deadline is not imminent.

National Institutes of Health · Up to $100K

This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.

National Institutes of Health · Up to $125K

This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports experienced individual scientists who want to redirect their research careers or gain new independent research skills in fields relevant to NIH's mission. It is an individual fellowship (awarded via a sponsoring institution), not a project grant for organizations, and eligibility text names foreign organizations as an other-eligible applicant category, which is unusual for NIH. No specific award amount is listed, and the deadline is set years out (2028), so there is no urgency to apply.

National Institutes of Health · Amount varies

This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students in combined MD/PhD or similar dual-doctoral degree programs at institutions that already have an NIH-funded dual-degree training program, preparing them for physician-scientist careers. It is limited to individual student applicants; foreign organizations and their non-U.S. components are not eligible, and applicants may not lead an independent clinical trial. No award amount is listed, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual predoctoral students conducting dissertation research in health-related fields under a faculty sponsor, with the goal of developing them into independent researchers. It is limited to individual applicants (not organizations); foreign organizations are named as an other-eligible category, and applicants may not lead an independent clinical trial. No specific award amount is listed, and the deadline is several years out.

National Institutes of Health · Up to $200K

This NIH R25 supports short courses that teach innovative research methods in the behavioral and social sciences, aimed at developing the biomedical research workforce. Eligible applicants are research institutions such as universities and minority- or tribal-serving colleges, with foreign organizations excluded. Awards go up to $200,000.

National Institutes of Health · Amount varies

This NIH R01 funds larger-scale research testing and disseminating interventions to improve health in Native American populations, following the same research focus as its companion R34 announcement. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with foreign entities restricted. No award amount is specified.

National Institutes of Health · Amount varies

This NIH R34 funds early-stage research and pilot studies testing interventions to improve health outcomes in Native American communities, including etiologic research and culturally-informed treatment studies. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with some restrictions on foreign entities. No award amount is specified; a clinical trial component is optional.

National Institutes of Health · Amount varies

This NIH R01 grant funds research applications studying the ethical, legal, and social implications of human genetics and genomics, using empirical, conceptual, legal, or normative methods. Applications must include a Plan for Enhancing Diverse Perspectives (PEDP); those without one won't be reviewed. It's aimed at eligible U.S. and territorial research institutions, and the deadline is November 18, 2026.

National Institutes of Health · Up to $50K

This NIH grant (up to $50,000) funds small research projects studying the ethical, legal, and social implications (ELSI) of human genetics and genomics, including single-investigator studies, preliminary data collection, and secondary data analysis. It's aimed at eligible U.S. and territorial research institutions. The deadline is November 16, 2026.

National Institutes of Health · Amount varies

This NIH R21 grant funds exploratory and developmental research into the ethical, legal, and social implications of human genetics and genomics, particularly studies examining new or emerging genomic technologies. It's open to eligible U.S. and territorial research institutions using empirical, conceptual, legal, or normative methods. The deadline is November 18, 2026.

National Institutes of Health · Amount varies

An NIH R34 funding formative research and pilot-testing of behavioral, social, structural, or combination interventions to improve HIV prevention and treatment for people who use drugs; a clinical trial is required. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is an early-stage clinical-research grant for investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH R36 award funds up to two years of doctoral dissertation research on substance use and substance use disorders, aligned with NIDA funding priorities, aimed at doctoral candidates across academic disciplines. Eligible U.S. institutions include HBCUs, tribal colleges, and minority-serving institutions; foreign organizations are not eligible. The deadline is September 7, 2026.

National Institutes of Health · Up to $150K

The NIDA Cutting-Edge Basic Research Award (CEBRA) funds highly innovative, high-risk basic research into substance use disorders that falls outside NIDA's typical portfolio. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations. Awards go up to $150,000.

National Institutes of Health · Up to $50K

The NIH parent Small Research Grant (R03, clinical trial not allowed) supports small, short-term projects such as pilot and feasibility studies, secondary data analysis, and methodology development. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget suits research institutions pursuing limited-scope projects to generate preliminary data.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial required) supports early-stage research projects with at least one clinical trial, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Up to $100K

This NIH (NIDA, R03) award helps investigators enter addiction-related data science, supporting small-scale projects that apply emerging data science methods or generate preliminary data for larger studies, with a budget cap around $100,000. Eligible applicants are research organizations including universities, colleges, government and tribal entities, and faith- or community-based organizations; it is intended for investigators at research institutions, not individuals or general nonprofits. It encourages use of existing datasets and FAIR principles. Confirm program-specific eligibility in the full announcement.

National Institutes of Health · Amount varies

This NIH research grant (R34) funds pilot and preliminary studies preparing for larger services-research trials on the treatment of drug, alcohol, and tobacco use disorders. It is intended for researchers at eligible institutions such as universities, nonprofits, tribal organizations, and government agencies. No award amount is listed, though R34 awards are typically modest pilot-scale budgets.

National Institutes of Health · Up to $375K

The REAP program funds small-scale research at health professional and graduate schools that haven't been major recipients of NIH support, while giving students hands-on research experience. Eligibility is limited to institutions awarding NIH-relevant degrees that received under $6 million per year in NIH support in 4 of the last 7 years — a specific financial threshold worth checking before applying. Awards go up to $375,000.

National Institutes of Health · Amount varies

This NIH (R01) opportunity funds innovative analysis of existing social, behavioral, administrative, and neuroimaging datasets to study substance-use behaviors, related disorders, prevention, and health-service use. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH (R21) opportunity funds innovative analysis of existing social, behavioral, administrative, and neuroimaging datasets to study substance-use behaviors, related disorders, prevention, and health-service use. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.

National Institutes of Health · Up to $375K

An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trials optional) supporting population-based research on how work and occupation influence health outcomes among populations with health disparities. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations, foreign components of U.S. organizations, and foreign components are not eligible. No specific award amount is stated. This suits research institutions conducting population health-disparities research.

National Institutes of Health · Amount varies

This NIH R01 funds studies testing innovative screening, brief intervention, and referral-to-treatment (SBIRT/P) approaches for alcohol, tobacco, and drug use in adult populations facing health disparities. Applicants should be research institutions collaborating with healthcare and community partners; eligible entities include universities, minority-serving institutions, and community organizations. No award amount is specified, and a clinical trial component is required.

National Institutes of Health · Amount varies

This NIH AREA (R15) award funds small-scale research at undergraduate-focused institutions that receive limited NIH funding, emphasizing undergraduate research experiences; a minimal-risk clinical trial is required. Eligible institutions must grant baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. No specific award amount is stated.

National Institutes of Health · Up to $300K

This NIH (R01) opportunity funds basic research into the harmful effects of acute exposure to ultra-potent synthetic opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations, including delayed effects. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $300,000.

National Institutes of Health · Up to $350K

This NIH/NIDA award funds research education programs that train clinicians and clinical researchers in substance use and substance use disorder research. Eligible applicants are research and education institutions, including HBCUs, Hispanic-serving and tribal-serving institutions, faith- or community-based organizations, and tribal governments; it is aimed at organizations, not individuals. Awards run up to about $350,000. Note the program supports research education only, not non-research clinical training, so review the stated scope carefully.

National Institutes of Health · Amount varies

This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.

National Institutes of Health · Amount varies

An NIH BRAIN Initiative R01 funding the development and validation of novel tools to study cell-type- and circuit-specific processes in the brain. Eligibility is geared toward research institutions, including HBCUs, Hispanic-serving and Tribal colleges, and foreign organizations; this is a federal research grant, not a fit for typical nonprofits, small businesses, or individuals without an academic/research affiliation. No award amount is specified. Clinical trials are not allowed under this opportunity.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative program (UG3/UH3) is a milestone-driven cooperative agreement supporting translational development and small clinical studies of next-generation therapeutic and diagnostic devices for nervous and neuromuscular disorders. Eligible applicants are institutions, including minority-serving institutions, HBCUs, and tribal colleges; foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components are otherwise allowed. NIH program staff participate in project planning and monitoring. No award amount is stated; eligibility centers on research institutions able to develop and test devices.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative program (UH3) funds small clinical trials to advance next-generation devices for recording and modulating the human central nervous system. Eligible applicants are institutions, including minority-serving institutions, HBCUs, and tribal colleges; foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components are otherwise allowed. No award amount is stated. This is a clinical-research mechanism aimed at research institutions capable of conducting device trials.

National Institutes of Health · Amount varies

This NIH R21 funds exploratory research on dissemination and implementation strategies for evidence-based health interventions, including studies on de-implementing low-value practices. Eligible applicants include universities and similar research institutions across NIH's mission areas. No award amount is specified.

National Institutes of Health · Up to $500K

An NIH UC2 program helping resource-limited organizations build biomedical research capacity and sponsored-programs administration. Eligible applicants include minority-serving and Tribal colleges and other domestic organizations with limited research resources; foreign organizations are not eligible. Awards reach up to about $500,000. This targets emerging or under-resourced research institutions rather than general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH R03 provides smaller, shorter-term funding for research on dissemination and implementation strategies — helping evidence-based health practices get adopted and sustained, or ineffective ones phased out. Eligible applicants include universities and similar research institutions across NIH's mission areas. No award amount is specified, though R03 awards are typically modest.

National Institutes of Health · Amount varies

This NIH R01 funds research identifying and testing strategies to help evidence-based health interventions get adopted, scaled, and sustained — or, conversely, to phase out ineffective practices. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations across NIH's mission areas. No award amount is specified.

National Institutes of Health · Amount varies

This NIH/Fogarty K43 career development award supports an early-career scientist at an academic or research institution in a low- or middle-income country, for research that does not involve leading an independent clinical trial. Eligibility is narrow and country-restricted: only foreign institutions in qualifying LMICs may apply, U.S. organizations and their foreign components are not eligible, and some upper-middle-income G20 countries are excluded. This is not available to U.S. applicants. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH/Fogarty K43 career development award supports an early-career scientist at an academic or research institution in a low- or middle-income country, with a required independent clinical trial. Eligibility is narrow and country-restricted: only foreign institutions in qualifying LMICs may apply, U.S. organizations and their foreign components are not eligible, and some upper-middle-income G20 countries are excluded. This is not available to U.S. applicants. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH program supports preclinical discovery and development of biologic-based therapies for nervous system disorders, from lead optimization through Phase I clinical testing. Eligible applicants are research organizations such as universities, colleges, government and tribal agencies, faith- or community-based organizations, and (for this announcement) foreign organizations; it is geared toward established research teams, not individuals or general nonprofits. Award amounts are not specified. Applicants should be prepared for a complex, multi-phase research undertaking with NIH-funded consultants and contract research organizations.

National Institutes of Health · Amount varies

This NIH (R13) program supports conferences and scientific meetings relevant to public health and the missions of participating NIH institutes. Eligible applicants are U.S. research and education organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Note that R13 conference support typically requires advance permission from the funding institute before applying. It is aimed at organizations hosting scientific conferences, not individuals. Award amounts are not specified.

National Institutes of Health · Amount varies

This NIH BRAIN Initiative (U24) program funds establishment of facilities at minority-serving institutions and IDeA-eligible institutions to produce and distribute brain cell type-specific research reagents to the neuroscience community. Eligibility is narrowed to minority-serving and IDeA-eligible U.S. institutions; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It is intended for qualifying research institutions, not individuals or general nonprofits, and awardees must coordinate with existing Armamentarium project teams. Award amounts are not specified.

National Institutes of Health · Up to $150K

An NIH Small Research Grant (I/START, R03) designed to help investigators enter brain-imaging research with small proof-of-concept studies relevant to substance use and addiction. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $150,000. It supports newly independent and established investigators through their institutions, not individuals applying directly.

National Institutes of Health · Amount varies

An NIDA U01 cooperative agreement funding animal-genomics research into variants linked to addiction and substance use disorders. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified, and clinical trials are not allowed. This is a federal research grant aimed at investigators, not general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R01 funding innovative research at the intersection of HIV and substance use, open to both individual investigators and research teams, and requiring a detailed research plan with preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is a research grant for investigators, not for general nonprofits, small businesses, or individuals without a research affiliation.

National Institutes of Health · Amount varies

This NIH R50 award provides salary support for established Research Software Engineers who build and disseminate biomedical software, tools, and algorithms. Eligible applicants include universities and research institutions; foreign (non-U.S.) organizations are not eligible to apply. It is tied to an existing research environment and specialized staff, so it suits research institutions rather than general nonprofits or individuals applying on their own. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH research education (R25) grant funds summer research experiences for high school or undergraduate students, or science teachers, tied to a participating institute's mission rather than general STEM. It is aimed at eligible institutions such as universities, nonprofits, and government agencies that would run the program; foreign organizations and foreign components are not allowed and clinical trials are not permitted. No award amount is listed.

National Institutes of Health · Up to $375K

This NIH R15 (AREA) award supports small-scale research at undergraduate-focused institutions that receive limited NIH funding, with a required clinical trial. Eligibility is restricted to institutions that award baccalaureate science degrees and have received no more than $6 million/year of NIH support in 4 of the last 7 years; foreign organizations are not eligible to apply. The maximum award is about $375,000. This is narrowly targeted at less-research-intensive degree-granting institutions.

National Institutes of Health · Amount varies

This NIH midcareer award (K24) provides protected time for mid-career clinician-scientists to conduct patient-oriented research and mentor junior clinical researchers; this version does not allow leading an independent clinical trial. It is intended for individual health-professional investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH midcareer award (K24) provides protected time for mid-career clinician-scientists to conduct patient-oriented research and mentor junior clinical researchers, and this version requires an independent clinical trial. It is intended for individual health-professional investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH Independent Scientist Award (K02) provides salary support and protected time for newly independent investigators to intensify their research focus; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development leading to research independence; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH Independent Scientist Award (K02) provides salary support and protected time for newly independent investigators to intensify their research focus, and this version requires leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development in biomedical, behavioral, or clinical research leading to independence, and this version requires an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

The NIH K99/R00 Pathway to Independence Award supports postdoctoral researchers transitioning to independent faculty positions, covering a mentored phase followed by several years of independent research funding. Applications are submitted through eligible research institutions — universities, minority-serving colleges, and similar organizations — on behalf of the individual awardee. No award amount is specified, and a clinical trial component is required for this version.

National Institutes of Health · Amount varies

The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.

National Institutes of Health · Amount varies

This NIH mentored career development award (K25) supports quantitative or engineering scientists redirecting their work toward health research, providing protected research time under a mentor; this version requires the applicant to lead an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mechanism provides emergency competitive revisions (supplemental funding) to existing NIH awards in response to declared disasters or public health emergencies. Only organizations that already hold a relevant NIH award and are responding to a specific Emergency Notice of Special Interest may apply, so it is limited to current NIH grantees rather than new applicants. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree committed to patient-oriented research, providing protected research time under mentorship, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree who are committed to patient-oriented research, providing protected research time under mentorship. This version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Up to $750K

An NIH BRAIN Initiative R18 funding preclinical proof-of-concept work on novel recording and modulation technologies for the human central nervous system, up to readiness for first-in-human studies. The eligibility text is mixed but states foreign organizations and foreign components are not eligible to apply, while domestic research institutions, minority-serving and Tribal colleges may. Awards reach up to about $750,000, and clinical trials are not allowed. This is a specialized research award, not a fit for general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $1.5M

An NIH RM1 funding team-based research at the intersection of HIV and substance use, requiring a detailed research plan and preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges; foreign organizations and foreign components are not eligible to apply. Awards reach up to about $1,500,000. This is a research-team grant for established investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $750K

NIH (NIDA) K12 institutional career-development funding to support mentored research training for clinician-scientists in substance use and substance use disorder research. Intended for institutions that will run a scholar training program; foreign organizations are not eligible and foreign components are not allowed. The listed maximum is about $750,000. This is an institutional training award, not a grant for individuals or general nonprofits.

National Institutes of Health · Amount varies

NIH mechanism allowing existing award recipients to apply for revision (supplemental) funding to expand a current NIH grant or cooperative agreement, only in response to a specific Notice of Special Interest. Restricted to organizations that already hold an active NIH single-project award. No award amount is specified. Because applicants must already be NIH grantees and respond to a matching NOSI, eligibility is narrow and not open to new applicants.

National Institutes of Health · Amount varies

This NIH X01 opportunity provides access to biospecimens (urine, plasma, serum, genomic DNA) and related data from the Population Assessment of Tobacco and Health (PATH) Study rather than direct research funding. It is aimed at investigators at universities, research institutions, and similar eligible organizations, including various minority-serving institutions and tribal entities. Foreign (non-U.S.) organizations and foreign components are not eligible. No award amounts are listed; this is a resource-access mechanism for researchers, not a general grant for nonprofits, businesses, or individuals.