INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across a…
- Deadline
- Jun 15, 2028
- Posted
- May 12, 2026
- Award amount
- Up to $500,000
- Focus areas
- Health
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We’ll email you before Jun 15, 2028 so you have time to apply.
In plain English
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
About this grant
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.
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