Diabetes, Digestive, and Kidney Diseases Extramural Research Grants (Assistance Listing 93.847)

National Institutes of Health · Up to $750K

An NIH P30 center grant funding shared research cores for digestive and liver diseases research. Only institutions with a strong existing research base, including at least $3 million per year in relevant direct-cost funding (with at least 30% from NIDDK), are eligible, so this effectively requires being an established, heavily NIH-funded institution. Foreign organizations are not eligible. Awards reach up to about $750,000. This is a narrow opportunity for major research centers, not for typical nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH (NIDDK) U24 cooperative agreement funds a single Research Coordinating Center to manage data, statistics, and operations for a consortium testing anti-obesity medication strategies in children and adolescents. Clinical trials are not allowed under this center role, and as a cooperative agreement NIH staff are substantially involved; this is a specialized coordinating-center award rather than a broad research grant. Foreign organizations, the foreign components of U.S. organizations, and foreign components are not eligible or allowed. No specific award amount is stated; see the NOFO for full eligibility details.

National Institutes of Health · Up to $1M

This NIH (NIDDK) U01 cooperative agreement funds clinical centers to join a consortium testing anti-obesity medication treatment strategies for children and adolescents with obesity. A clinical trial is required, and as a cooperative agreement NIH staff are substantially involved; applicants are typically clinical research institutions. Foreign organizations, the foreign components of U.S. organizations, and foreign components generally are not eligible or allowed. Stated funding is up to about $1,000,000; consult the NOFO for full eligibility details.

National Institutes of Health · Up to $500K

An NIH/NIDDK U01 continuing the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) consortium to study cardiovascular disease in people with type 1 diabetes. Foreign organizations and foreign components are not eligible to apply, and clinical trials are not allowed; it is tied to the existing consortium effort. Awards reach up to about $500,000. This is a specialized research-consortium award for investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $1.5M

This NIH (NIDDK) U24 cooperative agreement funds continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) Resource Center, supporting human cardiovascular tissue research. This is a single-source opportunity: only the University of Florida is eligible to apply, so no other organization qualifies. Foreign organizations and foreign components are not eligible, and clinical trials are not allowed under this mechanism. The stated maximum is about $1.5 million.

National Institutes of Health · Amount varies

This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH SBIR Phase IIB award is restricted to U.S. small business concerns that have previously received an NIH SBIR or STTR Phase II award; it bridges the gap between Phase II and commercialization for later-stage R&D. Only one such award is allowed per project, and applications must be submitted within the first six due dates after the Phase II budget period ends, so it is narrow and limited to existing grantees. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH SBIR/STTR Commercialization Readiness Pilot (CRP) is restricted to U.S. small business concerns (as defined by the SBA) and helps move NIH-funded SBIR/STTR projects from late-stage development toward commercialization. It supports later-stage R&D and technical assistance such as replication studies, IND/IDE-enabling work, clinical studies, manufacturing scale-up, and regulatory support, and a significant portion may be subcontracted. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Up to $2.2M

This NIH (NIDDK) U24 cooperative agreement funds continuation of the Integrated Islet Distribution Program, which supplies human islets to diabetes researchers. It is a single-source opportunity: only the PI/PDs associated with the prior award to Beckman Research Institute/City of Hope are eligible, so no other organization qualifies. Foreign organizations and foreign components are not eligible, and clinical trials are not allowed. The stated maximum is about $2.2 million.

National Institutes of Health · Amount varies

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R61/R33 funds milestone-driven development of clinical trials to treat co-occurring health conditions in people with Down syndrome — up to two years of planning followed by up to three years of trial support. Clinical trials are required.

National Institutes of Health · Up to $500K

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R01 funds groundbreaking, high-impact Down syndrome research across any relevant topic, with no preliminary data required. Awards up to about $500,000.

National Institutes of Health · Up to $2.1M

Open to U.S. research institutions and universities, nonprofits, and certain government/tribal organizations; foreign organizations cannot apply, and (as of May 2025) projects with foreign subawards are ineligible. This NIH U2C-TL1 funds institutional networks that recruit and train researchers in kidney, urologic, and hematologic disease research. Awards up to about $2,100,000.

National Institutes of Health · Up to $1M

An NIH/NIDDK P30 center grant funding shared research cores and a pilot/feasibility program for diabetes and related metabolic disease research. It is aimed at institutions with an established diabetes research base; only one application per institution is allowed, and foreign organizations are not eligible. Awards reach up to about $1,000,000. This is a center-scale research award for established institutions, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.

National Institutes of Health · Amount varies

This NIH R01 funds research examining the efficacy and clinical effectiveness of digital health technologies for the remote management of type 2 diabetes; a clinical trial is required. Eligible applicants include federal agencies, tribal governments, faith- or community-based organizations, regional organizations, and U.S. territories, in addition to standard research institutions. Foreign organizations and the foreign components of U.S. organizations are not eligible, and foreign components are not allowed. No specific award amount is stated in this record; see the NOFO for full eligibility details.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.

National Institutes of Health · Up to $100K

This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.

National Institutes of Health · Up to $125K

This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students in combined MD/PhD or similar dual-doctoral degree programs at institutions that already have an NIH-funded dual-degree training program, preparing them for physician-scientist careers. It is limited to individual student applicants; foreign organizations and their non-U.S. components are not eligible, and applicants may not lead an independent clinical trial. No award amount is listed, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship funds individual predoctoral students conducting dissertation research in health-related fields under a faculty sponsor, with the goal of developing them into independent researchers. It is limited to individual applicants (not organizations); foreign organizations are named as an other-eligible category, and applicants may not lead an independent clinical trial. No specific award amount is listed, and the deadline is several years out.

National Institutes of Health · Up to $200K

This NIH R25 supports short courses that teach innovative research methods in the behavioral and social sciences, aimed at developing the biomedical research workforce. Eligible applicants are research institutions such as universities and minority- or tribal-serving colleges, with foreign organizations excluded. Awards go up to $200,000.

National Institutes of Health · Amount varies

This NIH R01 funds larger-scale research testing and disseminating interventions to improve health in Native American populations, following the same research focus as its companion R34 announcement. Eligible applicants include universities, tribal colleges, minority-serving institutions, and community organizations, with foreign entities restricted. No award amount is specified.

National Institutes of Health · Up to $75K

A limited-competition NIH/NIDDK Small Grant (R03) available only to existing NIDDK-supported K01, K08, K23, and K25 career-award recipients, to support their transition to independent investigator status. A broad set of domestic and foreign institutions may apply on their behalf, but the underlying applicant must already hold a qualifying NIDDK K award. The grant is capped at about $75,000. This is restricted to current NIDDK career-award holders, not new applicants.

National Institutes of Health · Amount varies

This NIH/NIDDK R01 funds HIV/AIDS research aligned with NIDDK's mission and the NIH Office of AIDS Research priorities. Eligible applicants are research and education institutions, including minority-serving and tribal-serving institutions, faith- or community-based organizations, and tribal governments; it targets research organizations rather than individuals. No award amount is specified. Projects must fit the stated HIV/AIDS research priorities, so the scope is specific.

National Institutes of Health · Amount varies

This NIDDK (R21) opportunity funds basic and translational pilot research on biological, behavioral, and social mechanisms contributing to HIV pathogenesis within NIDDK's mission. It is intended for research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.

National Institutes of Health · Amount varies

Open to domestic institutions — universities, research institutions, nonprofits, and certain government/tribal organizations (foreign institutions are not eligible). This NIH T35 funds short-term (often summer) research-training experiences for health-professional and graduate students. It supports the institution's training program rather than an individual.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Up to $375K

An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.

National Institutes of Health · Amount varies

This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.

National Institutes of Health · Amount varies

This NIH SHINE (R01) opportunity supports innovative basic and early translational research in nonmalignant hematology, relevant to NIDDK, NIA, and NHLBI missions. It is intended for research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH R01 funds research identifying and testing strategies to help evidence-based health interventions get adopted, scaled, and sustained — or, conversely, to phase out ineffective practices. Eligible applicants include universities, minority- and tribal-serving institutions, and similar research organizations across NIH's mission areas. No award amount is specified.

National Institutes of Health · Up to $350K

This NIH HEAL Initiative R61/R33 funds early translational drug-discovery research toward non-addictive pain therapeutics, including assay development, screening, and initial characterization of candidate agents; no clinical trial is allowed. Eligible applicants include universities, research institutions, and tribal and community organizations, but foreign organizations are not eligible to apply. The maximum award is about $350,000. It requires drug-discovery research capacity.

National Institutes of Health · Amount varies

This NIH R50 award provides salary support for established Research Software Engineers who build and disseminate biomedical software, tools, and algorithms. Eligible applicants include universities and research institutions; foreign (non-U.S.) organizations are not eligible to apply. It is tied to an existing research environment and specialized staff, so it suits research institutions rather than general nonprofits or individuals applying on their own. No specific award amount is stated.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development leading to research independence; this version does not allow leading an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored research scientist award (K01) provides three to five years of protected, supervised career development in biomedical, behavioral, or clinical research leading to independence, and this version requires an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

The NIH K99/R00 Pathway to Independence Award supports postdoctoral researchers transitioning to independent faculty positions, covering a mentored phase followed by several years of independent research funding. Applications are submitted through eligible research institutions — universities, minority-serving colleges, and similar organizations — on behalf of the individual awardee. No award amount is specified, and a clinical trial component is required for this version.

National Institutes of Health · Amount varies

The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.

National Institutes of Health · Amount varies

This NIH mentored career development award (K25) supports quantitative or engineering scientists redirecting their work toward health research, providing protected research time under a mentor; this version requires the applicant to lead an independent clinical trial. It is intended for individual investigators applying through eligible institutions such as universities. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree committed to patient-oriented research, providing protected research time under mentorship, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree who are committed to patient-oriented research, providing protected research time under mentorship. This version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.