Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)
This NIH (NIDDK) U01 cooperative agreement funds clinical centers to join a consortium testing anti-obesity medication treatment strategies for children and adolescents with obesity. A clinical tri…
- Deadline
- Oct 9, 2026
- Posted
- Jun 8, 2026
- Award amount
- Up to $1,000,000
- Focus areas
- Health
Don’t miss this deadline
We’ll email you before Oct 9, 2026 so you have time to apply.
In plain English
This NIH (NIDDK) U01 cooperative agreement funds clinical centers to join a consortium testing anti-obesity medication treatment strategies for children and adolescents with obesity. A clinical trial is required, and as a cooperative agreement NIH staff are substantially involved; applicants are typically clinical research institutions. Foreign organizations, the foreign components of U.S. organizations, and foreign components generally are not eligible or allowed. Stated funding is up to about $1,000,000; consult the NOFO for full eligibility details.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
About this grant
This Notice of Funding Opportunity (NOFO) invites applications from clinical centers to participate in a consortium to test anti-obesity medication (AOM) treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs. Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will collaborate on the development of protocols, use of common measures and data elements, use of a central laboratory and standardized procedures to collect data and biospecimens, and data analyses and manuscripts. This NOFO uses a cooperative agreement mechanism (U01) and runs in parallel with a companion NOFO (RFA-DK-27-136).
Let AI draft your application
Your first draft is free: a narrative and budget outline tailored to this grant, emailed to you. Drafts are written in a nightly batch, so it arrives by email later — not instantly on this page.
Application Kit — $49 one-time
Winner intelligence + a first-draft narrative grounded in applications that actually won. One payment, no subscription.
Get the Application Kit →Related grants
Other open grants funding Health — soonest deadline first.
Alcohol Health Services Research (R01 Clinical Trial Optional)
National Institutes of Health · Up to $500K · Due in 17 days
Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)
National Institutes of Health · Up to $500K · Due in 17 days
Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
National Institutes of Health · Up to $500K · Due Oct 1, 2026
In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
National Institutes of Health · Up to $500K · Due Oct 1, 2026
Alcohol Health Services Research (R34 Clinical Trial Optional)
National Institutes of Health · Amount varies · Due in 17 days
Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)
National Institutes of Health · Amount varies · Due in 17 days
Also listed under National Institutes of Health and Health Grants.
Source: public records via Grants.gov. UseGrants is an independent aggregator, not affiliated with any funding agency. Always confirm details on the official listing before applying.