Biomedical Research and Research Training Grants (Assistance Listing 93.859)

National Institutes of Health · Amount varies

This NIH award is open only to U.S. institutions located in IDeA-eligible states/jurisdictions (a fixed list including Alaska, Arkansas, Delaware, Hawaii, Kentucky, Mississippi and others) that grant doctoral degrees in health-related sciences or are NIH-funded biomedical research institutes. It funds the expansion and sustainability of existing Centers of Biomedical Research Excellence, building faculty, research projects, and core facilities. Eligibility is narrow: it is a limited competition by invitation, applicants may hold no more than three active COBRE awards, and foreign organizations and foreign components are not eligible.

National Institutes of Health · Amount varies

This NIH Predoctoral-to-Postdoctoral Transition Award (F99/K00) supports promising graduate students as they finish doctoral research and move into mentored postdoctoral career development, in NIH mission-relevant fields. It is a mentored training award administered through institutions; candidates may not lead an independent clinical trial but may participate in a sponsor-led one. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25/UE5) funds mentoring activities and networks that develop the biomedical, behavioral, and clinical research workforce. It requires institutional commitment of staff, facilities, and resources, and proposed activities must be distinct from any existing federally funded training programs (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds hands-on research experiences that help build and diversify the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can provide the staff, facilities, and educational resources to run such programs, and proposed activities must be distinct from any existing federally funded training grants (such as T32). Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH Research Education Program (R25) funds the development of courses, curricula, and educational methods that strengthen the biomedical, behavioral, and clinical research workforce. It is aimed at institutions that can commit staff, facilities, and educational resources, and proposed activities must be distinct from any existing federally funded training grants (such as T32) at the applicant. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

This NIH/NIGMS RM1 grant funds Biomedical Technology Optimization and Dissemination Centers to refine late-stage research technologies and sustainably share them with the wider biomedical research community. Applicants should be leaders in their technology field and within the NIGMS mission. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.

National Institutes of Health · Amount varies

This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · Amount varies

This NIH SBIR Phase IIB award is restricted to U.S. small business concerns that have previously received an NIH SBIR or STTR Phase II award; it bridges the gap between Phase II and commercialization for later-stage R&D. Only one such award is allowed per project, and applications must be submitted within the first six due dates after the Phase II budget period ends, so it is narrow and limited to existing grantees. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH SBIR/STTR Commercialization Readiness Pilot (CRP) is restricted to U.S. small business concerns (as defined by the SBA) and helps move NIH-funded SBIR/STTR projects from late-stage development toward commercialization. It supports later-stage R&D and technical assistance such as replication studies, IND/IDE-enabling work, clinical studies, manufacturing scale-up, and regulatory support, and a significant portion may be subcontracted. Foreign organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.

National Institutes of Health · $25K–$250K

This NIH S10 instrumentation grant funds resource-limited institutions to purchase state-of-the-art scientific instruments supporting biomedical research and education. It is a limited competition that invites applications only from eligible organizations, and awards range from about $25,000 to $250,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.

National Institutes of Health · Amount varies

This NIH/NIGMS award (MIRA for Early Stage Investigators) funds early-career biomedical researchers at U.S. institutions to run an independent research program aligned with the NIGMS mission. It is aimed at Early Stage Investigators, so it is restrictive by career stage. Non-U.S. (foreign) institutions and foreign components of U.S. organizations are not eligible to apply, though foreign components within projects may be allowed per NIH policy.

National Institutes of Health · Amount varies

The NIH Science Education Partnership Award (SEPA, R25) funds educational projects that increase understanding of biomedical research among pre-college (pre-K through grade 12) students and encourage interest in STEM careers. It suits universities, research institutions, and education-focused organizations that can run science education programs. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted.

National Institutes of Health · Amount varies

An NIH R24 supporting National Centers for Cryo-electron Tomography that provide shared access to advanced cryoET instrumentation and training. It targets established research institutions able to run a national core facility; foreign organizations and foreign components are not eligible. No award amount is specified, and clinical trials are not allowed. This is a narrow research-infrastructure award, not suited to typical nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH/NIGMS T34 training grant funds undergraduate-enrolling institutions to build biomedical research training and mentoring programs that prepare students for PhD or MD/PhD careers. Eligibility is restrictive: applicant institutions must enroll undergraduates and have averaged less than $50M per year in NIH Research Project Grant funding over the last three fiscal years. Foreign institutions and foreign components of U.S. organizations are not eligible to apply.

National Institutes of Health · Amount varies

Open to eligible NIGMS-funded investigators and new investigators at U.S. institutions; foreign organizations are not eligible, and projects with foreign subawards are excluded. This NIH R35 (MIRA) gives an investigator stable, flexible single-grant support for their lab's research within the NIGMS mission, rather than project-by-project funding. Early-stage investigators should use the separate ESI MIRA notice.

National Institutes of Health · Amount varies

This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.

National Institutes of Health · Amount varies

Open specifically to federally recognized American Indian/Alaska Native tribes, tribal colleges and universities, tribal health programs, and tribal organizations. This NIH R34 planning grant funds preparatory work to develop competitive Native American Research Centers for Health (NARCH) applications. Eligibility is narrow — limited to AI/AN tribal entities; award size follows standard R34 limits.

National Institutes of Health · Up to $100K

This NIH award (SuRE, up to $100,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited higher education institutions who do not currently hold other NIH research project grants, aiming to build research capacity and student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is under $100,000, and the application deadline is not imminent.

National Institutes of Health · Up to $125K

This NIH award (SuRE-First, up to $125,000) funds investigator-initiated biomedical research by full-time faculty at resource-limited institutions who have never previously held an independent, peer-reviewed external research grant, aiming to build research capacity and provide student research experience. Foreign organizations and their non-U.S. components are not eligible. The maximum award is small, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports predoctoral students pursuing a combined MD/PhD or similar dual-doctoral degree at institutions that lack an NIH-funded dual-degree training program, aiming to prepare them for physician-scientist careers. It applies to individual students, not organizations, and excludes foreign organizations and their non-U.S. components; applicants cannot lead an independent clinical trial. No funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH fellowship supports experienced individual scientists who want to redirect their research careers or gain new independent research skills in fields relevant to NIH's mission. It is an individual fellowship (awarded via a sponsoring institution), not a project grant for organizations, and eligibility text names foreign organizations as an other-eligible applicant category, which is unusual for NIH. No specific award amount is listed, and the deadline is set years out (2028), so there is no urgency to apply.

National Institutes of Health · Amount varies

This NIH fellowship funds individual postdoctoral researchers who show strong potential to become independent investigators in health-related research fields, supporting mentored research training. It is an individual award (not for organizations), and foreign organizations are listed as an other-eligible applicant category. No specific funding amount is given, and the deadline is not imminent.

National Institutes of Health · Amount varies

This NIH R24 funds operation of specialized national or regional research resources — equipment, technologies, software, or services — serving a broad multi-state or national biomedical research community. It's aimed at established research institutions capable of maintaining and staffing shared infrastructure, not general nonprofits or businesses. No award amount is specified.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Up to $650K

This NIH limited-competition award (UG3/UH3) funds collaborative innovation projects within the CTSA Program consortium to accelerate translational research. Eligibility is restricted per the funding notice, and foreign organizations and their U.S. components are not eligible, so this is aimed at institutions already in or aligned with the CTSA consortium rather than the general public. Awards run up to roughly $650,000. Review the notice's eligibility section closely, as access is limited.

National Institutes of Health · Up to $375K

An NIH Academic Research Enhancement Award (AREA/R15) for undergraduate-focused institutions that do not receive substantial NIH funding, supporting small-scale biomedical research with undergraduate involvement. Eligibility is narrow: institutions must award baccalaureate science degrees and have received no more than about $6 million per year of NIH support in 4 of the last 7 years; foreign organizations are not eligible. The award is capped at about $375,000. This is restricted to qualifying lower-NIH-funded undergraduate institutions.

National Institutes of Health · Amount varies

This NIH training grant funds domestic institutions of higher education (including HBCUs, Hispanic-serving institutions, and tribal colleges) to build predoctoral and postdoctoral biomedical research training programs, not individual researchers directly. Eligibility is fairly broad among institution types, but non-domestic entities and their foreign components are excluded, and the program does not support short-term-only training plans. No dollar amount is listed, and the deadline is not near-term.

National Institutes of Health · Amount varies

This NIH award funds research projects developing new technologies to advance biomedical knowledge acquisition, aimed at institutions including HBCUs, Hispanic-serving institutions, and tribal colleges, among others. Foreign organizations and their non-U.S. components are not eligible to apply. No specific dollar amount is listed, and the deadline is not imminent.

National Institutes of Health · Up to $500K

An NIH UC2 program helping resource-limited organizations build biomedical research capacity and sponsored-programs administration. Eligible applicants include minority-serving and Tribal colleges and other domestic organizations with limited research resources; foreign organizations are not eligible. Awards reach up to about $500,000. This targets emerging or under-resourced research institutions rather than general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH High-End Instrumentation (HEI) program funds groups of NIH-supported investigators to purchase or upgrade a single piece of high-end research instrumentation, with awards ranging from a minimum of $750,001 up to $2,000,000. Eligible applicants are U.S. research institutions, including minority-serving institutions and tribally controlled colleges; foreign organizations and their components are not eligible and foreign components are not allowed. Note a key restriction: applicants must have groups of existing NIH-supported investigators, so this is not for individuals, new organizations, or general nonprofits. This is a large-award instrumentation grant for established research institutions.

National Institutes of Health · Amount varies

This NIH Basic Instrumentation Grant (BIG) program funds groups of NIH-supported investigators to purchase a single specialized research instrument, with awards from $25,000 up to $350,000. Eligibility is limited to U.S. institutions that have not received $500,001 or more in S10 instrumentation funding in the preceding three fiscal years; foreign organizations and their components are not eligible and foreign components are not allowed. It requires groups of existing NIH-supported investigators, so it is not for individuals, new organizations, or general nonprofits. This is an instrumentation grant for less-funded research institutions.

National Institutes of Health · Amount varies

This NIH Shared Instrumentation Grant (SIG) program funds groups of NIH-supported investigators to purchase or upgrade a single specialized research instrument, with awards from $50,000 up to $750,000. Eligible applicants are U.S. research institutions, including minority-serving and tribally controlled colleges; foreign organizations and their components are not eligible and foreign components are not allowed. It requires groups of existing NIH-supported investigators, so it is not for individuals, new organizations, or general nonprofits. This is a large-award instrumentation grant for established research institutions.

National Institutes of Health · Amount varies

This NIH (R13) program supports conferences and scientific meetings relevant to public health and the missions of participating NIH institutes. Eligible applicants are U.S. research and education organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Note that R13 conference support typically requires advance permission from the funding institute before applying. It is aimed at organizations hosting scientific conferences, not individuals. Award amounts are not specified.

National Institutes of Health · Amount varies

An NIH UE5/T32 award that funds federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to build graduate-level research training in AI/AN health. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible. No award amount is specified. This is a narrow opportunity limited to Tribal applicants and is not a fit for other nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH UE5/T34 award funding federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to develop undergraduate-level research training in AI/AN health. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible. No award amount is specified. Like its T32 counterpart, this is narrow and not a fit for non-Tribal nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R24 funding federally recognized American Indian/Alaska Native Tribes, Tribal colleges, Tribal health programs, and Tribal organizations to establish or strengthen Tribal Institutional Review Boards. Eligibility is restricted to qualifying Tribal entities; foreign organizations are not eligible, and clinical trials are not allowed. No award amount is specified. This is narrow and not a fit for non-Tribal nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $350K

This NIH program (S15) helps eligible academic or research institutions buy modern equipment to modernize shared-use biomedical research facilities such as core labs and animal research facilities. Eligible applicants are institutions, including minority-serving institutions, HBCUs, and tribal colleges; foreign organizations and foreign components are not eligible. The award ceiling is about $350,000, and the program does not fund scientific research instruments themselves or building-level infrastructure. This is institution-focused support, not for individuals or general organizations.

National Institutes of Health · Up to $500K

This NIH (NIGMS) R25 supports organizations developing educational and skills-training programs for the biomedical research workforce, with activities open to the broader research community and spanning career stages from undergraduates to faculty and staff scientists. Eligible applicants include higher-education institutions, nonprofits, tribal governments, faith- or community-based organizations, and federal agencies; independent clinical trials are not allowed. Foreign organizations and the foreign components of U.S. organizations are not eligible, and foreign components are not allowed. Stated funding is up to about $500,000.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific NIH grants and need to transfer an award due to a change in organizational status (successor-in-interest). It is an administrative prior-approval request, not a new funding opportunity, and approval of the transfer is not guaranteed. Only current NIH grantee organizations should use it; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.

National Institutes of Health · Amount varies

This NIH Pathway to Independence award (K99/R00) supports outstanding postdoctoral researchers transitioning to independent faculty positions; this version does not allow leading an independent clinical trial. It is intended for individual early-career investigators applying through eligible institutions such as universities; foreign organizations cannot apply. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

The NIH K25 award supports quantitative scientists and engineers (e.g., in math, statistics, computer science, or physics) who want to redirect their research toward NIH-relevant health questions, providing protected time for mentored study. It's submitted through eligible research institutions on behalf of an individual investigator, and excludes those leading an independent clinical trial. No award amount is specified.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree committed to patient-oriented research, providing protected research time under mentorship, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree who are committed to patient-oriented research, providing protected research time under mentorship. This version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.

National Institutes of Health · Amount varies

An NIH/NIGMS T32 award funding domestic institutions to run Medical Scientist Training Programs that train dual-degree (MD/PhD or equivalent) physician-scientists. Eligible applicants include domestic research institutions, minority-serving and Tribal colleges; foreign institutions and foreign components are not eligible. No award amount is specified. This is an institutional training grant for established medical/research institutions, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH T32 grant funds institutional predoctoral training programs in basic biomedical sciences, supporting didactic coursework, research experience, and career development for graduate trainees. It's aimed at eligible U.S. research and training institutions (HBCUs and tribal colleges included). The deadline is September 25, 2026.

U.S. National Science Foundation · $100K–$250K

This joint NSF/NIH opportunity funds science-of-science research analyzing and improving the biomedical research enterprise, drawing on social, behavioral, and economic science methods. Eligibility is stated as unrestricted (open to any eligible entity type), so check the solicitation for the specific organization categories allowed; NSF awards typically go to institutions on behalf of investigators. The stated award range is roughly $100,000 to $250,000. This is a research-focused opportunity.

U.S. National Science Foundation · $1–$1.2M

This joint NSF/NIH initiative funds fundamental mathematics and statistics research aimed at answering questions in the biological and biomedical sciences, with two tracks supporting projects up to roughly $600,000 or $1,200,000 over 3-4 years. Eligibility is stated as unrestricted (open to any eligible entity type), so review the solicitation for the specific organization categories allowed; in practice NSF awards go to institutions on behalf of investigators. The program encourages new and existing interdisciplinary collaborations. Award amounts can reach the large-award range.