National Institutes of Health Grants
654 open grant opportunities from National Institutes of Health, from Grants.gov — each with a plain-English summary of who qualifies, the deadline, and the award size.
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)
Due May 7, 2027National Institutes of Health · Amount varies
This NIH midcareer award (K24) provides protected time for mid-career clinician-scientists to conduct patient-oriented research and mentor junior clinical researchers, and this version requires an independent clinical trial. It is intended for individual health-professional investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityRisk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH R01 funds research on risk and protective factors in family health, well-being, and resilience, aimed at reducing health disparities through family-level interventions. Eligible applicants include universities, minority- and tribal-serving institutions, and community organizations, with restrictions on foreign entities. No award amount is specified.
ResearchersBroad eligibilityMentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K23) supports individuals with a clinical doctoral degree committed to patient-oriented research, providing protected research time under mentorship, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research; this version does not allow leading an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityMentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)
Due May 8, 2027National Institutes of Health · Amount varies
This NIH mentored career development award (K08) prepares individuals with a clinical doctoral degree for research careers through supervised biomedical, behavioral, or translational research, and this version requires an independent clinical trial. It is intended for individual clinician-investigators applying through eligible institutions such as universities and academic medical centers. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityNIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)
Due May 26, 2027National Institutes of Health · Up to $200K
This NIH/NIA research education (R25) grant funds summer research education programs in Alzheimer's disease and related dementias for high school students, undergraduates, or science teachers. The listed eligible applicants are limited to a narrow set of organizations (faith- or community-based organizations, certain tribal governments, regional organizations, and U.S. territories), and foreign organizations and components are not allowed. The listed budget cap is about $200,000, and participants may not lead an independent clinical trial.
Schools & universitiesResearchersNarrow eligibilitySmall awardNIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)
Due May 26, 2027National Institutes of Health · Up to $400K
This NIH/NIA research education (R25) grant funds postbaccalaureate research education programs in Alzheimer's disease and related dementias to broaden the research workforce. The listed eligible applicants are limited to a narrow set of organizations (faith- or community-based organizations, certain tribal governments, regional organizations, and U.S. territories), and foreign organizations and components are not allowed. The listed budget cap is about $400,000.
Schools & universitiesResearchersNarrow eligibilityLimited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
Due May 28, 2027National Institutes of Health · Amount varies
This is a limited-competition NIH/NCATS research education (R25) grant supporting education programs within the Clinical and Translational Science Award (CTSA) program. Because it is a limited competition, eligibility is restricted to specific invited institutions rather than open to all applicants; foreign organizations are not eligible. No award amount is listed, and the eligibility text is narrow and does not fully specify which organizations may apply.
Schools & universitiesResearchersNarrow eligibilityHigh-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
Due Jun 1, 2027National Institutes of Health · Amount varies
This NIH High-End Instrumentation (HEI) program funds groups of NIH-supported investigators to purchase or upgrade a single piece of high-end research instrumentation, with awards ranging from a minimum of $750,001 up to $2,000,000. Eligible applicants are U.S. research institutions, including minority-serving institutions and tribally controlled colleges; foreign organizations and their components are not eligible and foreign components are not allowed. Note a key restriction: applicants must have groups of existing NIH-supported investigators, so this is not for individuals, new organizations, or general nonprofits. This is a large-award instrumentation grant for established research institutions.
ResearchersSchools & universitiesLarge awardNarrow eligibilityLimited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)
Due Jun 1, 2027National Institutes of Health · Amount varies
This NIH Basic Instrumentation Grant (BIG) program funds groups of NIH-supported investigators to purchase a single specialized research instrument, with awards from $25,000 up to $350,000. Eligibility is limited to U.S. institutions that have not received $500,001 or more in S10 instrumentation funding in the preceding three fiscal years; foreign organizations and their components are not eligible and foreign components are not allowed. It requires groups of existing NIH-supported investigators, so it is not for individuals, new organizations, or general nonprofits. This is an instrumentation grant for less-funded research institutions.
ResearchersSchools & universitiesNarrow eligibilityShared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
Due Jun 1, 2027National Institutes of Health · Amount varies
This NIH Shared Instrumentation Grant (SIG) program funds groups of NIH-supported investigators to purchase or upgrade a single specialized research instrument, with awards from $50,000 up to $750,000. Eligible applicants are U.S. research institutions, including minority-serving and tribally controlled colleges; foreign organizations and their components are not eligible and foreign components are not allowed. It requires groups of existing NIH-supported investigators, so it is not for individuals, new organizations, or general nonprofits. This is a large-award instrumentation grant for established research institutions.
ResearchersSchools & universitiesLarge awardNarrow eligibilityEnhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
Due Jun 2, 2027National Institutes of Health · Amount varies
This NIH (R61/R33) phased opportunity funds mechanistic research to advance precision probiotic therapies, beginning with an exploratory phase to identify person-specific factors and a second phase to test them in animal models or human subjects, over a combined period of up to five years. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. Transition between phases depends on meeting milestones. It is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityEnhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
Due Jun 2, 2027National Institutes of Health · Amount varies
This NIH (R33) opportunity funds mechanistic research to advance precision probiotic therapies by characterizing person-specific factors that affect probiotic responses, using animal models or human subjects. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It expects supportive preliminary data and is intended for established research teams, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityNIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)
Due Jun 14, 2027National Institutes of Health · Amount varies
This NIH R24 funds operation of specialized national or regional research resources — equipment, technologies, software, or services — serving a broad multi-state or national biomedical research community. It's aimed at established research institutions capable of maintaining and staffing shared infrastructure, not general nonprofits or businesses. No award amount is specified.
ResearchersNarrow eligibilityBRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
Due Jun 15, 2027National Institutes of Health · Amount varies
This NIH BRAIN Initiative (U01) program funds development of next-generation sensors and bioelectronic devices that synchronize with brain recordings to build computational models of human and animal behavior. Eligible applicants are research organizations including universities, colleges, government and tribal entities, and faith- or community-based organizations; it targets established research and technology-development teams, not individuals or general nonprofits. Award amounts are not specified. Confirm program-specific eligibility in the full announcement.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityBRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
Due Jun 15, 2027National Institutes of Health · Amount varies
This NIH BRAIN Initiative (U24) program funds establishment of facilities at minority-serving institutions and IDeA-eligible institutions to produce and distribute brain cell type-specific research reagents to the neuroscience community. Eligibility is narrowed to minority-serving and IDeA-eligible U.S. institutions; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It is intended for qualifying research institutions, not individuals or general nonprofits, and awardees must coordinate with existing Armamentarium project teams. Award amounts are not specified.
ResearchersSchools & universitiesNarrow eligibilityEarly-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)
Due Jun 17, 2027National Institutes of Health · Amount varies
This NIH (NIDCD, R21) opportunity is a planned re-issue to support early-stage dissemination and implementation research in hearing, balance, taste, smell, voice, speech, and language. For this announcement foreign organizations and non-U.S. components are eligible to apply, but NIH will not issue awards involving foreign subawards/subcontracts unless submitted under a specifically designated international-collaboration announcement. Note the announcement states applications are not being solicited at this time, so it is a notice of intent rather than an open call. It is intended for research institutions, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityPreclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
Due Jul 2, 2027National Institutes of Health · Amount varies
This NIH (R21) opportunity funds preclinical efficacy studies in established rare-disease models to demonstrate that a candidate therapeutic warrants further development, including supporting pharmacokinetic and pharmacodynamic studies. Eligible applicants are U.S. research organizations including universities, government and tribal entities, and faith- or community-based organizations; foreign organizations and non-U.S. components are not eligible to apply, though some foreign components are allowed. It is intended for research teams advancing therapeutic candidates, not individuals or general nonprofits. Award amounts are not specified.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibilityNHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)
Due Jul 12, 2027National Institutes of Health · Amount varies
This NIH (NHLBI) career transition award helps postdoctoral fellows in NHLBI's intramural research division move their research programs to outside (extramural) institutions, supporting a mentored intramural phase followed by an extramural phase. Eligibility is narrow: it is tied to candidates currently in the NHLBI Division of Intramural Research, and applications come through eligible U.S. institutions; foreign organizations and their components are not eligible and foreign components are not allowed. This is not open to general researchers, individuals, or nonprofits without that intramural connection. Award amounts are not specified.
ResearchersSchools & universitiesNarrow eligibilityChange of Recipient Organization (Type 7 Parent Clinical Trial Optional)
Due Jul 12, 2027National Institutes of Health · Amount varies
This NIH mechanism is narrowly limited to organizations that already hold specific types of NIH grants and need to transfer an existing award to a new recipient institution (a change of recipient organization). It is an administrative prior-approval request, not a new funding opportunity, and there is no guarantee a transfer will be approved. Only current NIH grantee organizations should apply; it does not apply to individuals, new applicants, or general nonprofits. No award amount applies.
ResearchersSchools & universitiesGovernment / tribalNarrow eligibility
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How many National Institutes of Health grants are open right now?
UseGrants is tracking 654 open National Institutes of Health opportunities. The next one closes May 7, 2027. The largest published award ceiling on this page is $400,000. The list is rebuilt from public records daily, so an opportunity drops off it the day its deadline passes.
Who can apply for National Institutes of Health funding?
Eligibility is set per opportunity, not per agency — the same funder will run one program open to any nonprofit and another restricted to accredited universities. Across the National Institutes of Health opportunities listed here the recurring eligibility signals are researchers, schools & universities, narrow eligibility and broad eligibility. Every listing still states its own terms in plain English; confirm them on the funder's official notice before you apply.