National Institutes of Health Grants
654 open grant opportunities from National Institutes of Health, from Grants.gov — each with a plain-English summary of who qualifies, the deadline, and the award size.
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Due Feb 8, 2027National Institutes of Health · Amount varies
An NIH BRAIN Initiative R01 funding the development and validation of novel tools to study cell-type- and circuit-specific processes in the brain. Eligibility is geared toward research institutions, including HBCUs, Hispanic-serving and Tribal colleges, and foreign organizations; this is a federal research grant, not a fit for typical nonprofits, small businesses, or individuals without an academic/research affiliation. No award amount is specified. Clinical trials are not allowed under this opportunity.
ResearchersSchools & universitiesNarrow eligibilitySilvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
Due Feb 10, 2027National Institutes of Health · Up to $750K
An NIH P30 center grant funding shared research cores for digestive and liver diseases research. Only institutions with a strong existing research base, including at least $3 million per year in relevant direct-cost funding (with at least 30% from NIDDK), are eligible, so this effectively requires being an established, heavily NIH-funded institution. Foreign organizations are not eligible. Awards reach up to about $750,000. This is a narrow opportunity for major research centers, not for typical nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesLarge awardNarrow eligibilityNIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Due Feb 11, 2027National Institutes of Health · Amount varies
An NIDA U01 cooperative agreement funding animal-genomics research into variants linked to addiction and substance use disorders. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified, and clinical trials are not allowed. This is a federal research grant aimed at investigators, not general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesNarrow eligibilityBRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)
Due Feb 11, 2027National Institutes of Health · Up to $700K
An NIH BRAIN Initiative R61 funding exploratory human neuroscience using invasive neural recording and stimulation during surgical procedures. Foreign organizations and foreign components are not eligible; the work requires multidisciplinary teams with access to neurosurgical settings. Awards reach up to about $700,000, and clinical trials are not allowed. This is a highly specialized research award for institutions with relevant clinical/research capacity, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesLarge awardNarrow eligibilitySupporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
Due Feb 26, 2027National Institutes of Health · Amount varies
An NIH/NHGRI R01 supporting early-stage investigators pursuing genomics research, across genomic sciences, medicine, data science, and ethical/legal/social implications. Foreign organizations are not eligible; domestic research institutions, minority-serving and Tribal colleges may apply, and the program targets researchers in an early-career stage. No award amount is specified. This is a research grant for academic/early-career investigators, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesNew orgs OKNarrow eligibilityAccelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)
Due Mar 1, 2027National Institutes of Health · Amount varies
An NIH X01 award giving researchers access to stored All of Us biospecimens (plasma, serum, DNA) to run assays and add data back to the program. It is aimed at scientific investigators, including foreign organizations, who can conduct multiomics and biomarker analyses; it is a resource-access award rather than a general grant. No dollar amount is specified, and clinical trials are not allowed. Not a fit for nonprofits, small businesses, or individuals outside the research community.
ResearchersNarrow eligibilityNIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Due Mar 4, 2027National Institutes of Health · Amount varies
An NIH/NIAMS UG3/UH3 cooperative agreement funding the implementation of clinical trials, where a clinical trial is required. The eligibility text is internally mixed but states that foreign organizations and foreign components of U.S. organizations are not eligible to apply, while domestic research institutions, minority-serving and Tribal colleges may apply. No award amount is specified. This is a clinical-research award for institutions equipped to run trials, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesNarrow eligibilityDiscovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
Due Mar 5, 2027National Institutes of Health · Amount varies
An NIH R01 funding discovery and optimization of in vivo chemical probes for novel nervous-system targets, with applicants expected to already have validated starting compounds and bioassays in hand. Domestic and foreign organizations and foreign components are eligible to apply. No award amount is specified, and clinical trials are not allowed. This is a research grant for investigators with existing medicinal-chemistry capacity, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesNarrow eligibilityHigh Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)
Due Mar 5, 2027National Institutes of Health · Up to $1.5M
An NIH RM1 funding team-based research at the intersection of HIV and substance use, requiring a detailed research plan and preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges; foreign organizations and foreign components are not eligible to apply. Awards reach up to about $1,500,000. This is a research-team grant for established investigators, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesLarge awardNarrow eligibilityHigh Priority HIV and Substance Use Research (R01 Clinical Trial Optional)
Due Mar 6, 2027National Institutes of Health · Amount varies
An NIH R01 funding innovative research at the intersection of HIV and substance use, open to both individual investigators and research teams, and requiring a detailed research plan with preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is a research grant for investigators, not for general nonprofits, small businesses, or individuals without a research affiliation.
ResearchersSchools & universitiesNarrow eligibilityOpportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
Due Mar 6, 2027National Institutes of Health · Up to $500K
An NIH U01 supporting collaborative translational research conducted with NIH intramural investigators using the NIH Clinical Center. Domestic and foreign organizations may apply, but NIH will not fund awards involving foreign subawards/subcontracts under this opportunity, so applications relying on foreign subawards are excluded. Awards reach up to about $500,000. This is a research grant for investigators able to partner with NIH, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesLarge awardNarrow eligibilityContinuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)
Due Mar 10, 2027National Institutes of Health · Up to $500K
An NIH/NIDDK U01 continuing the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) consortium to study cardiovascular disease in people with type 1 diabetes. Foreign organizations and foreign components are not eligible to apply, and clinical trials are not allowed; it is tied to the existing consortium effort. Awards reach up to about $500,000. This is a specialized research-consortium award for investigators, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesLarge awardNarrow eligibilityDevelopment and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)
Due Mar 16, 2027National Institutes of Health · Amount varies
An NIH R34 funding formative research and pilot-testing of behavioral, social, structural, or combination interventions to improve HIV prevention and treatment for people who use drugs; a clinical trial is required. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is an early-stage clinical-research grant for investigators, not for general nonprofits, small businesses, or individuals.
ResearchersSchools & universitiesNarrow eligibilityNIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
Due Apr 5, 2027National Institutes of Health · Amount varies
This NIH STTR program (R41/R42) funds U.S. small businesses that partner with a nonprofit research institution to move scientific innovations toward commercialization. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.
Small businessNarrow eligibilityNIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
Due Apr 5, 2027National Institutes of Health · Amount varies
This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.
Small businessNarrow eligibilityShort Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
Due Apr 9, 2027National Institutes of Health · Up to $200K
This NIH R25 supports short courses that teach innovative research methods in the behavioral and social sciences, aimed at developing the biomedical research workforce. Eligible applicants are research institutions such as universities and minority- or tribal-serving colleges, with foreign organizations excluded. Awards go up to $200,000.
ResearchersSchools & universitiesComputational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)
Due Apr 15, 2027National Institutes of Health · Up to $250K
This NIH/NLM research grant funds development of computational, at-scale approaches to curate biomedical research data and models. It is aimed at researchers at institutions such as universities, nonprofits, and other eligible organizations; foreign organizations are not eligible. The listed budget cap is about $250,000, and clinical trials are not allowed under this opportunity.
ResearchersSchools & universitiesSmall awardEmergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)
Due Apr 18, 2027National Institutes of Health · Amount varies
This NIH mechanism provides emergency competitive revisions (supplemental funding) to existing NIH awards in response to declared disasters or public health emergencies. Only organizations that already hold a relevant NIH award and are responding to a specific Emergency Notice of Special Interest may apply, so it is limited to current NIH grantees rather than new applicants. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibilityEnvironmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
Due Apr 20, 2027National Institutes of Health · Amount varies
This NIH/NIEHS center grant (P30) funds Environmental Health Sciences Core Centers that provide shared research infrastructure, facilities, and services to groups of environmental health researchers. It is intended for established research institutions such as universities with existing groups of independently funded investigators; foreign organizations cannot apply. No award amount is listed. This center mechanism is not suited to individual applicants or new organizations.
ResearchersSchools & universitiesNarrow eligibilityNHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)
Due Apr 28, 2027National Institutes of Health · Amount varies
This NIH/NHLBI award supports established researchers conducting heart, lung, blood, and sleep research, providing long-term program funding for up to seven years. Applicants must already be the lead investigator on at least two NHLBI R01-equivalent awards, so it is limited to existing NHLBI grantees rather than new investigators. Applications come through eligible institutions such as universities, hospitals, and research organizations; foreign organizations cannot apply. No award amount is listed.
ResearchersSchools & universitiesNarrow eligibility
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How many National Institutes of Health grants are open right now?
UseGrants is tracking 654 open National Institutes of Health opportunities. The next one closes Feb 8, 2027. The largest published award ceiling on this page is $1,500,000. The list is rebuilt from public records daily, so an opportunity drops off it the day its deadline passes.
Who can apply for National Institutes of Health funding?
Eligibility is set per opportunity, not per agency — the same funder will run one program open to any nonprofit and another restricted to accredited universities. Across the National Institutes of Health opportunities listed here the recurring eligibility signals are researchers, schools & universities, narrow eligibility and large award. Every listing still states its own terms in plain English; confirm them on the funder's official notice before you apply.