National Institutes of Health Grants
654 open grant opportunities from National Institutes of Health, from Grants.gov — each with a plain-English summary of who qualifies, the deadline, and the award size.
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
Due Nov 16, 2027National Institutes of Health · Amount varies
This NIH (R01) opportunity funds research developing novel screening approaches or therapies for fatal or disabling conditions identified through newborn screening, including high-priority genetic conditions. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityBasic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
Due Nov 16, 2027National Institutes of Health · Amount varies
This NIH (R21) opportunity funds basic, mechanistic research into the biological and genetic causes of cancer health disparities, including new methods, models, and secondary data analyses. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityChemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
Due Nov 18, 2027National Institutes of Health · Up to $300K
This NIH (R01) opportunity funds basic research into the harmful effects of acute exposure to ultra-potent synthetic opioids (e.g., fentanyl, carfentanil, nitazenes) and their combinations, including delayed effects. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $300,000.
ResearchersSchools & universitiesNarrow eligibilityAccelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Due Dec 3, 2027National Institutes of Health · Amount varies
This NIH (R01) opportunity funds innovative analysis of existing social, behavioral, administrative, and neuroimaging datasets to study substance-use behaviors, related disorders, prevention, and health-service use. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityAccelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
Due Dec 3, 2027National Institutes of Health · Amount varies
This NIH (R21) opportunity funds innovative analysis of existing social, behavioral, administrative, and neuroimaging datasets to study substance-use behaviors, related disorders, prevention, and health-service use. It is intended for research and academic institutions rather than individuals or general nonprofits/small businesses. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityCatalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)
Due Dec 23, 2027National Institutes of Health · Amount varies
This NHLBI Catalyze (R61/R33) phased opportunity funds medical device prototype design and testing, disease-target identification, and assay development for heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityCatalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)
Due Dec 23, 2027National Institutes of Health · Amount varies
This NHLBI Catalyze (R33) opportunity funds early-stage translational work to optimize medical device prototypes, develop diagnostic assays, and create research tools for heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityCatalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)
Due Dec 23, 2027National Institutes of Health · Up to $350K
This NHLBI Catalyze (R33) opportunity funds rigorous validation of transformative, multi-use platforms or technologies that can advance detection, diagnosis, treatment, or prevention of heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $350,000.
ResearchersSchools & universitiesNarrow eligibilityCatalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)
Due Dec 23, 2027National Institutes of Health · Amount varies
This NHLBI Catalyze (R61/R33) phased opportunity funds target identification and validation plus preliminary product or lead-series identification for small molecules, biologics, and combination products treating heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityCatalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
Due Dec 23, 2027National Institutes of Health · Amount varies
This NHLBI Catalyze (R33) opportunity funds early-stage translational work to identify and characterize therapeutic candidates and combination products (small molecules and biologics) for heart, lung, blood, and sleep diseases. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityNIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Amount varies
This NIDCR (UG3/UH3) cooperative agreement funds planning and implementation of drug, biologic, device, or procedure intervention clinical trials within NIDCR's mission. A clinical trial is required. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityStimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
Due Jan 6, 2028National Institutes of Health · Amount varies
This NIH SHINE (R01) opportunity supports innovative basic and early translational research in nonmalignant hematology, relevant to NIDDK, NIA, and NHLBI missions. It is intended for research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityContinuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Amount varies
This NIDCR (UH3) opportunity funds competing renewal or competitive revision of ongoing clinical trials already supported by NIDCR; a clinical trial is required. Because it continues existing NIDCR-funded trials, it is effectively limited to current grantees and not open to new projects. It is aimed at research and academic institutions; foreign organizations are not eligible. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityNIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Due Jan 6, 2028National Institutes of Health · Up to $500K
This NIDCR (UG3/UH3) cooperative agreement funds planning and implementation of behavioral and social intervention clinical trials for dental, oral, or craniofacial conditions, with a milestone-driven planning phase before transition to a full trial. A clinical trial is required. It is aimed at research and academic institutions; foreign organizations are not eligible. The maximum award is about $500,000.
ResearchersSchools & universitiesLarge awardNarrow eligibilityNIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Up to $50K
The NIH parent Small Research Grant (R03, clinical trial not allowed) supports small, short-term projects such as pilot and feasibility studies, secondary data analysis, and methodology development. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget suits research institutions pursuing limited-scope projects to generate preliminary data.
ResearchersSchools & universitiesGovernment / tribalNonprofits+2 moreDevelopment of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Up to $200K
This NIH ORIP (R21) opportunity funds research to develop, improve, and preserve animal models and related biological materials with broad applicability across multiple NIH institutes; single-disease or single-institute projects are out of scope. It is aimed at research and academic institutions; foreign organizations are not eligible. The maximum award is about $200,000.
ResearchersSchools & universitiesNarrow eligibilityDevelopment of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)
Due Jan 7, 2028National Institutes of Health · Amount varies
This NIH (R61/R33) opportunity funds discovery and early evaluation of candidate biomarkers for neurological and neuromuscular disorders, requiring preliminary human-sample evaluation. It is aimed at research and academic institutions; foreign organizations are not eligible to apply. No specific award amount is stated.
ResearchersSchools & universitiesNarrow eligibilityThe Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)
Due Jan 7, 2028National Institutes of Health · Amount varies
An NIH research project grant (R01, clinical trials optional) supporting population-based research on how work and occupation influence health outcomes among populations with health disparities. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations, foreign components of U.S. organizations, and foreign components are not eligible. No specific award amount is stated. This suits research institutions conducting population health-disparities research.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreScreening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)
Due Jan 7, 2028National Institutes of Health · Amount varies
An NIH research project grant (R01, clinical trial not allowed) supporting screening and functional validation of genomic variants linked to human congenital anomalies, developmental disabilities, and inborn errors of metabolism. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science genomics mechanism for research institutions.
ResearchersSchools & universitiesGovernment / tribalNonprofits+1 moreMechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
Due Jan 7, 2028National Institutes of Health · Up to $500K
This NCI (R01) opportunity funds investigator-initiated studies on the mechanisms by which bariatric surgery affects cancer risk. It is intended for research and academic institutions; foreign organizations are not eligible to apply. The maximum award is about $500,000.
ResearchersSchools & universitiesLarge awardNarrow eligibility
Page 13 of 33
How many National Institutes of Health grants are open right now?
UseGrants is tracking 654 open National Institutes of Health opportunities. The next one closes Nov 16, 2027. The largest published award ceiling on this page is $500,000. The list is rebuilt from public records daily, so an opportunity drops off it the day its deadline passes.
Who can apply for National Institutes of Health funding?
Eligibility is set per opportunity, not per agency — the same funder will run one program open to any nonprofit and another restricted to accredited universities. Across the National Institutes of Health opportunities listed here the recurring eligibility signals are researchers, schools & universities, narrow eligibility and large award. Every listing still states its own terms in plain English; confirm them on the funder's official notice before you apply.