Grants for Nonprofits

National Institutes of Health · Amount varies

This NIH/NCI R01 funds advanced preclinical research translating nanotechnology-based cancer diagnostics and therapeutics toward later NCI translational programs; no clinical trial is allowed. Eligible applicants are research and education institutions, including minority-serving and tribal-serving institutions, faith- or community-based organizations, and tribal governments; it targets research organizations, not individuals. Foreign organizations are not eligible. No award amount is specified, and the nanomedicine focus makes the scope narrow.

Dept of the Army -- Materiel Command · Amount varies

This U.S. Army Research Laboratory Broad Agency Announcement solicits foundational (basic and applied) research proposals supporting Army modernization. Eligibility is broad, including universities, nonprofits, state and local governments, foreign organizations, and for-profit firms (large and small businesses). It uses a competitive merit-based process; no specific award amount is stated.

Environmental Protection Agency · $0–$3M

This EPA program funds assessment and remediation of contaminated Alaska Native Claims Settlement Act lands, plus related community outreach. Eligibility is limited to Alaska Native regional and village corporations, federally recognized Tribes in Alaska, Alaska Native nonprofit associations, and inter-tribal consortia of Alaskan tribal entities. The maximum award is up to about $3,000,000, and proposals are accepted on a rolling basis; applicants are asked to contact program managers first.

Dept of the Army -- Materiel Command · Amount varies

This U.S. Army DEVCOM Analysis Center Broad Agency Announcement solicits applied-research proposals supporting Army modernization, tool development, and data curation. Eligibility is broad, including universities, nonprofits, state and local governments, foreign organizations, and for-profit firms (large and small businesses). It uses a whitepaper-then-proposal process; no specific award amount is stated.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding pilot effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions running pilot effectiveness studies.

National Institutes of Health · Up to $200K

An NIH/NCMRR Early Career Research Award (R03, clinical trial optional) supporting basic and clinical rehabilitation research from scientists establishing independent careers, intended to generate preliminary data for a later R01. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $200,000. This is an early-career research mechanism administered through a sponsoring institution.

National Institutes of Health · Up to $150K

An NIH/NEI planning grant (R34, clinical trial not allowed) supporting development of study protocols and manuals of procedures for future clinical vision research, including trials and epidemiologic studies. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $150,000. Funds cannot be used to generate intervention-effect data, so this is a planning mechanism for research institutions.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding effectiveness trials of post-acute therapeutic and service-delivery interventions for mental health conditions across the lifespan. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and faith- or community-based organizations. No specific award ceiling is stated. This requires conducting a clinical trial, so it suits research institutions with that capacity rather than individuals or general nonprofits.

National Institutes of Health · Up to $50K

An NIH/NICHD Small Research Grant (R03, clinical trial required) supporting small clinical-trial projects within the NICHD mission. Eligible applicants include a broad range of domestic and foreign institutions such as universities, tribal governments, and community-based organizations. The award is capped at about $50,000. The small budget and clinical-trial requirement make this best suited to research institutions running limited-scope pilot trials.

National Institutes of Health · Amount varies

An NIH/NIMH planning grant (R34, clinical trial required) funding research on family-navigation emergency-department diversion models for non-urgent mental health concerns. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. No specific award amount is stated. This requires a clinical trial and suits research institutions in mental health services research.

National Institutes of Health · Amount varies

An NIH/NIMH research project grant (R01, clinical trial required) funding research on family-navigation emergency-department diversion models for non-urgent mental health concerns. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components are not eligible. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions in mental health services research.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial not allowed) supporting screening and functional validation of genomic variants linked to human congenital anomalies, developmental disabilities, and inborn errors of metabolism. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science genomics mechanism for research institutions.

National Institutes of Health · Amount varies

A limited-competition NIH planning grant (R34, clinical trial not allowed) supporting fundamental research on skin injuries caused by chemical threats and potential shared therapeutic targets. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components of U.S. organizations are not eligible, though foreign components within the project are allowed. No specific award amount is stated. As a limited competition, eligibility may be further restricted beyond the listed categories, so review the NOFO closely.

National Institutes of Health · Amount varies

An NIH/NCI exploratory grant (R21, clinical trial not allowed) funding proof-of-concept studies on the mechanisms by which bariatric surgery affects cancer risk. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. Projects must address feasibility not already established in the literature, so this suits research institutions with relevant preliminary direction.

National Institutes of Health · Up to $75K

A limited-competition NIH/NIDDK Small Grant (R03) available only to existing NIDDK-supported K01, K08, K23, and K25 career-award recipients, to support their transition to independent investigator status. A broad set of domestic and foreign institutions may apply on their behalf, but the underlying applicant must already hold a qualifying NIDDK K award. The grant is capped at about $75,000. This is restricted to current NIDDK career-award holders, not new applicants.

National Institutes of Health · Amount varies

An NIH/NCI exploratory/developmental bioengineering research grant (EBRG, R21, clinical trial optional) funding feasibility-stage projects that develop new capabilities or improvements for biomedical, pre-clinical, or clinical research and care. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a bioengineering research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

An NIH/NIDCD dissertation fellowship (F32) supporting Au.D. audiologists pursuing rigorous biomedical research training and dissertation research toward a research doctorate. A broad range of domestic and foreign institutions may apply as the sponsoring organization, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an individual fellowship mechanism administered through a sponsoring institution, aimed at audiologist trainees.

National Institutes of Health · Amount varies

An NIH/NCI exploratory/developmental bioengineering research grant (EBRG, R21, clinical trial not allowed) funding feasibility-stage projects that develop new capabilities or improvements for biomedical, pre-clinical, or clinical research and care. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a bioengineering research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.