Grants for Nonprofits

DOC NOAA - ERA Production · $0

This NOAA Office of Oceanic and Atmospheric Research (OAR) Broad Agency Announcement invites applications for special projects aligned with NOAA's strategic plan and mission. Eligibility is broad and includes higher-education institutions, nonprofits, commercial organizations, international or foreign organizations and governments, individuals, and state, local, and tribal governments, though eligibility for a given activity depends on NOAA's statutory authority. Federal organizations are generally outside the scope. No award amount is provided, and as a BAA this describes a general framework rather than a single defined award; review the announcement for specifics.

Office of Science · $50K–$5M

The DOE Office of Science runs this open, year-round solicitation supporting research across program areas including advanced scientific computing, basic energy sciences, biological and environmental research, fusion energy, high energy physics, nuclear physics, and isotope R&D. Eligibility is described as unrestricted (open to any entity type), subject to clarifications and to the requirements in 10 CFR 605. Awards range from roughly $50,000 to $5 million. The NOFO remains open until September 30, 2026 or until succeeded by a new issuance.

Fish and Wildlife Service · $1–$750K

The U.S. Fish and Wildlife Service Partners for Fish and Wildlife Program funds habitat restoration and protection on private lands (including tribal, municipal, and non-governmental properties), mainly through cooperative agreements. Eligible projects must be on private lands and align with regional strategic plans; 501(c)(3) organizations should have IRS proof of status, and tribal applicants may need an authorizing resolution. All applicants are required to contact local PFW staff before applying. The stated maximum is about $750,000.

National Institutes of Health · Amount varies

This NIH (NIDCD) award funds Clinical Research Center Grants (P50) advancing diagnosis, prevention, and treatment of hearing, balance, smell, taste, voice, speech, or language disorders. Eligible applicants are domestic research-capable organizations, including higher-education institutions, nonprofits, tribal governments, faith-based or community organizations, and U.S. territories; foreign organizations are not eligible to apply, though foreign components may be allowed. A low-risk clinical trial is optional, not required. No dollar range is stated, and applicants should read the NOFO closely and contact NIDCD staff before applying.

National Institutes of Health · Amount varies

This NIH R01 funds research examining the efficacy and clinical effectiveness of digital health technologies for the remote management of type 2 diabetes; a clinical trial is required. Eligible applicants include federal agencies, tribal governments, faith- or community-based organizations, regional organizations, and U.S. territories, in addition to standard research institutions. Foreign organizations and the foreign components of U.S. organizations are not eligible, and foreign components are not allowed. No specific award amount is stated in this record; see the NOFO for full eligibility details.

National Institutes of Health · Up to $250K

This NIH (NCI) UH3 award funds the clinical validation of already analytically validated molecular, cellular, or imaging biomarker assays for cancer detection, diagnosis, prognosis, monitoring, and treatment response, using specimens from clinical trials or studies. Eligible applicants include higher-education institutions, nonprofits, tribal governments, and federal agencies; clinical trials are not allowed and early-stage technology development is out of scope. Applicants must already have an analytically validated assay, which narrows who can realistically apply. Foreign organizations and foreign components of U.S. organizations are not eligible to apply; stated funding is around $250,000.

National Institutes of Health · Amount varies

This NIH (NCI) UH2/UH3 award funds both analytical and clinical validation of molecular, cellular, or imaging biomarker assays for cancer detection, diagnosis, prognosis, monitoring, and treatment response. Eligible applicants include higher-education institutions, nonprofits, tribal governments, and federal agencies; clinical trials are not allowed and applicants should already have assays that work on human samples. Foreign organizations and the foreign components of U.S. organizations are not eligible to apply, though some foreign components are allowed. No specific award amount is stated in this record.

National Institutes of Health · Up to $500K

This NIH (NIGMS) R25 supports organizations developing educational and skills-training programs for the biomedical research workforce, with activities open to the broader research community and spanning career stages from undergraduates to faculty and staff scientists. Eligible applicants include higher-education institutions, nonprofits, tribal governments, faith- or community-based organizations, and federal agencies; independent clinical trials are not allowed. Foreign organizations and the foreign components of U.S. organizations are not eligible, and foreign components are not allowed. Stated funding is up to about $500,000.

National Institutes of Health · Amount varies

This NIH (NCI) award funds revision applications to clinically validate biomarker assays that were originally developed through existing NIH-supported research grants, meaning applicants generally need an active or prior NCI-supported assay to revise. Eligible applicants include higher-education institutions, nonprofits, tribal governments, and federal agencies; clinical trials are not allowed and early-stage technology development is out of scope. Because it builds on prior NIH funding, eligibility is effectively narrow. No specific award amount is stated in this record.

Agricultural Marketing Service · $250K–$1M

This USDA Agricultural Marketing Service program funds collaborative multi-state partnerships that enhance the competitiveness of U.S. specialty crops through projects addressing regional or national issues such as food safety, plant pests and disease, research, and marketing. Eligible applicants are federally recognized tribal governments, state governments, public and state-controlled higher-education institutions, and 501(c)(3) nonprofits other than institutions of higher education. Projects must benefit two or more states or territories. Awards range from about $250,000 to $1,000,000.

National Institutes of Health · Up to $300K

This NIH (CounterACT) R01 funds basic research on how chemical warfare agents, toxic industrial chemicals, and pesticides affect the nervous system, aimed at understanding toxicity mechanisms and identifying therapeutic targets. Eligible applicants include higher-education institutions, nonprofits, tribal governments, faith- or community-based organizations, and federal agencies; clinical trials are not allowed. Foreign (non-U.S.) organizations and the foreign components of U.S. organizations are not eligible to apply. The award appears to be roughly $300,000 in stated funding.

Bureau of Land Management · $30K–$220K

This Bureau of Land Management program funds Qualified Youth Corps organizations to run natural and cultural resource projects on public lands employing youth ages 16 to 30 (veterans up to 35), including tribal members. Individuals and for-profit organizations are explicitly ineligible, so this is aimed at nonprofit/qualified youth corps entities. Note an important restriction: applicants seeking to hire interns or crews under the Public Lands Corps Act must instead apply under a separate companion NOFO (15.243). Award amounts range from about $30,000 to $220,000.

U.S. National Science Foundation · Amount varies

This NSF INCLUDES program funds collaborative, national-scale efforts to broaden participation and build inclusive infrastructure in STEM, supporting pilots, consortia, alliances, network connectors, and conferences. Eligibility is relatively broad: for-profit organizations including small businesses, nonprofit non-academic organizations, state and local governments, institutions of higher education, and federally recognized tribal nations may apply. No specific award amounts are listed. This is a research and capacity-building opportunity open to a range of organizations, though not to individuals.

National Institute of Standards and Technology · Amount varies

This NIST CHIPS Incentives Program funds construction, expansion, or modernization of commercial facilities for semiconductor materials and manufacturing equipment. Applicants must be a 'covered entity,' defined as a nonprofit, private-sector entity, or a consortium of such entities with demonstrated ability to substantially finance and build large semiconductor-related facilities. This is aimed at established firms and consortia capable of major capital projects, not individuals, researchers, or small or new organizations; applications go through the CHIPS Incentives Portal. No award amounts are specified, but the program targets large-scale industrial projects.

Defense Health Agency Contracting Activity - DHACA · Amount varies

Department of War (Defense Health Agency) Rare Cancers Research Program Resource and Community Development Award funding the creation of research resources, datasets, and infrastructure to advance rare cancers research. Eligibility is listed as unrestricted/open to any entity type subject to clarification in the full notice; preliminary data are not required, but patient-advocate engagement and dissemination plans are. No award amount is specified. The stated eligibility is broad.

U.S. National Science Foundation · Amount varies

NSF FINDERS FOUNDRY program funding partnerships of K-12 educators, technologists, and researchers to develop technology-based solutions to learning and workforce challenges, with a focus on early AI exposure. Eligible applicants are limited to US nonprofits/non-academic research organizations, state and local governments, US institutions of higher education, and federally recognized tribal nations; unaffiliated individuals cannot apply and no PI degree is required. Only teams awarded planning grants may later submit development proposals. No award amount is specified.

Office of the Assistant Secretary for Health · $200K–$22M

This Title X program funds voluntary family planning services across U.S. states and territories. Eligible applicants are broad and include state, local, and tribal governments, public and private institutions of higher education, public housing authorities, and nonprofits with or without 501(c)(3) status. Awards are large, with individual amounts running into the millions and roughly $257 million expected across about 90 awards. The work must deliver clinical family planning services to low-income and uninsured populations, so applicants generally need health-service delivery capacity.

U.S. National Science Foundation · $5K–$47.5M

This NSF program supports procurement, upgrade, and operation of shared-use oceanographic facilities and equipment, primarily research vessels and related infrastructure. Eligibility is limited to U.S.-based nonprofit non-academic research organizations and institutions of higher education acting for their faculty. Awards range widely from about $5,000 to $47.5 million depending on the activity. Many of these facilities also receive partial support from other sources, so cost-sharing or proportional support arrangements are common; applicants should review the solicitation.

U.S. National Science Foundation · Amount varies

This NSF program funds Antarctic and Southern Ocean research that does not require U.S. Antarctic Program field support, including data/sample-based studies and analogue-site work. Eligibility is limited to U.S.-based nonprofit non-academic research organizations, institutions of higher education acting for their faculty, and federally recognized tribal nations. It is aimed at researchers and academic or research institutions. No specific award amount is stated.

Department of Housing and Urban Development · $112.5K–$250K

A HUD program providing one-time, cost-reimbursable grants for service coordination and limited direct services to residents of HUD-assisted housing facing emergencies such as natural disasters or public-health crises. Eligible applicants include public/Indian housing authorities, nonprofits (with or without 501(c)(3) status, including resident associations), multifamily owners, Tribal governments and entities, and faith-based organizations, so eligibility is relatively broad among housing-connected organizations. Awards run roughly $112,500 to $250,000. Note that funds are reimbursed after costs are incurred and serve HUD-assisted housing residents specifically.