45 private foundations reported health & medical grants in South Carolina on their IRS Form 990-PF filings for tax years 2023–2025. Historical giving records — not an open application portal.
Themes are derived from the free-text purpose each foundation wrote on its own Part XV filing, so a grant is classified by what the funder said it was for. Grants paid directly to named individuals are excluded from recipient counts and tables.
Across tax years 2023–2025, 45 private foundations reported 197 grants for health & medical totaling $34,501,408 to 116 organizations in South Carolina. The most-funded South Carolina communities were Charleston, Columbia, Greenville. The Duke Endowment reported the most health & medical giving — $25,993,158 across 99 grants. The median grant was $100,000.
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| Foundation | Grants | Total |
|---|---|---|
| The Duke Endowment | 99 | $25,993,158 |
| BlueCross BlueShield of South Carolina Foundation | 22 | $4,414,137 |
| The Plymouth Rock Assurance Foundation | 1 | $654,500 |
| Chris and DEE DEE Gibson Foundation | 1 | $500,000 |
| DR Miriam & Sheldon G Adelson Medical Research Foundation | 1 | $402,106 |
| Charles a Cannon Charitable Trust NO 3 | 1 | $300,470 |
| Carequest Foundation Inc | 2 | $280,000 |
| William Randolph Hearst Foundation | 2 | $250,000 |
| The Big D Foundation | 1 | $175,000 |
| AC3 Foundation Inc | 1 | $166,667 |
| The Byerly Foundation | 2 | $155,050 |
| Yawkey Foundation | 5 | $125,000 |
| Recipient | Grants | Total |
|---|---|---|
| Medical University of South Carolina Foundation | 30 | $9,054,212 |
| University of South Carolina Educational Foundation | 18 | $4,193,000 |
| South Carolina Hospital Association Foundation | 3 | $2,321,000 |
| Health Sciences South Carolina | 1 | $1,634,000 |
| Scha Foundation | 2 | $1,520,000 |
| Mcleod Health Foundation | 6 | $1,493,000 |
| South Carolina Institute of Medicine and Public Health | 4 | $1,000,000 |
| University of South Carolina | 2 | $720,896 |
| SC Research Foundation | 1 | $695,898 |
| Spartanburg Regional Healthcare System Foundation | 5 | $664,500 |
| Blackbaud Giving Fund | 1 | $654,500 |
| Conway Medical Center | 4 | $595,000 |
| USC Educational Foundation | 1 | $540,000 |
| SC Department of Alcohol and Other Drug Abuse Serv | 1 | $488,025 |
| Roper ST Francis Foundation | 2 | $450,000 |
45 private foundations reported health & medical grants in South Carolina on their IRS Form 990-PF filings, totaling $34,501,408. The largest by reported dollars were The Duke Endowment, BlueCross BlueShield of South Carolina Foundation, The Plymouth Rock Assurance Foundation. These are historical filings, not open application portals — check each foundation's own guidelines before approaching them.
116 distinct organizations appear as recipients in South Carolina, led by Medical University of South Carolina Foundation, University of South Carolina Educational Foundation, South Carolina Hospital Association Foundation. Grants paid directly to named individuals are excluded from these figures.
The median reported health & medical grant in South Carolina was $100,000, and the largest single reported grant was $1,634,000. Amounts are as reported by the filing foundation for a historical tax year.
The UseGrants feed tracks federal and state opportunities that are open today, each with the eligibility explained in plain English.
Source: public IRS Form 990-PF Part XV filings (tax years 2023–2025). Theme classification is derived from the funder’s own purpose text and is a summary, not a legal categorization. UseGrants is an independent aggregator, not affiliated with any foundation listed.
