Browse grants

National Institutes of Health · Amount varies

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH R61/R33 funds milestone-driven development of clinical trials to treat co-occurring health conditions in people with Down syndrome — up to two years of planning followed by up to three years of trial support. Clinical trials are required.

National Institutes of Health · Amount varies

Open specifically to federally recognized American Indian/Alaska Native tribes, tribal colleges and universities, tribal health programs, and tribal organizations. This NIH R34 planning grant funds preparatory work to develop competitive Native American Research Centers for Health (NARCH) applications. Eligibility is narrow — limited to AI/AN tribal entities; award size follows standard R34 limits.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R21 funds projects that improve clinical-trial readiness for rare diseases — developing biomarkers and outcome measures, or characterizing a disease's course to enable future trials. Award size follows standard R21 limits.

Defense Health Agency Contracting Activity - DHACA · $750K–$50M

Open broadly to any type of entity — universities, nonprofits, businesses (including small businesses), and others. This Department of Defense / Defense Health Agency broad agency announcement funds extramural biomedical and human-performance research and development through FY28. Awards span a very wide range, from about $750,000 to $50 million.

Washington Headquarters Services · $2.5K–$800K

This Department of Defense program funds research on security cooperation and irregular warfare topics, open to individual researchers (with or without institutional affiliation), academic institutions, think tanks, and federally funded R&D centers; past awardees may reapply. Applicants can submit only one proposal at a time as principal investigator, and research products must be unclassified and made publicly accessible. Awards range from $2,500 to $800,000, and the deadline is not imminent.

National Institutes of Health · Up to $3M

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH UG3/UH3 funds discovery and development of interventions — medications and devices — to prevent and treat substance use disorders and overdose, including preclinical and clinical studies. Awards up to about $3,000,000.

National Institutes of Health · Up to $500K

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 funds development of non-invasive or minimally invasive technologies to image the human olfactory system at high resolution. Awards up to about $500,000; multidisciplinary teams are encouraged.

National Institutes of Health · Amount varies

Open to U.S. universities, research institutions, nonprofits, and certain government/tribal organizations; foreign organizations are not eligible. This NIH R01 supports early-stage investigators pursuing a new research direction, and applications must include no preliminary data. Award size follows standard R01 limits; aimed at researchers early in their independent careers.

Food and Drug Administration · $225K–$2.5M

This FDA grant (U18, $225,000 to $2,500,000) funds veterinary diagnostic laboratories in the Vet-LIRN network to build capacity for animal food safety and antimicrobial resistance testing, including equipment and method development. Eligibility is broad, covering nonprofits (with or without 501(c)(3) status), small businesses, for-profit organizations, universities, tribal governments, and state/local governments. No unusual disqualifiers are noted, and the deadline is not imminent.

National Institutes of Health · Amount varies

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH/NCI R21 funds early-stage, exploratory research on cancer control — prevention behaviors, screening, etiology, and novel methods. Award size follows standard R21 limits.

National Institutes of Health · Amount varies

Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH DP1 (Avant-Garde/Avenir) funds high-risk, high-reward research on HIV and substance use — basic, clinical, translational, or implementation science. It backs bold, transformative ideas; award size follows the DP1 mechanism.

Department of Health · Up to $2.5M

The New York State Department of Health's Drinking Water Fluoridation RFA funds eligible NYS municipalities to plan (Component A) or implement/maintain (Component B) community water fluoridation systems, with awards up to $2,500,000, on a rolling submission basis. While listed eligibility includes for-profit, governmental, and not-for-profit entities, the program description specifically targets NYS municipalities, so applicants should confirm municipal eligibility before applying. The deadline is September 28, 2028.

National Institutes of Health · Up to $400K

This NIH R01 grant funds research into early immune system development from the prenatal period through early childhood, including effects of in-utero HIV or antiretroviral exposure. A broad range of applicants is eligible, including colleges and universities, tribal governments, faith- and community-based organizations, minority-serving institutions, and foreign organizations. The award ceiling is up to about $400,000.

Employment and Training Administration · $150K–$10M

This U.S. Department of Labor program provides National Dislocated Worker Grants to help communities respond to layoffs and disasters that displace workers. Eligibility is restricted to government and workforce entities such as state workforce agencies, local Workforce Development Boards, outlying areas, and Indian tribal governments, depending on the grant type; individual nonprofits and businesses are not direct applicants. Awards are large, ranging from about $150,000 up to roughly $10M.

Dept of the Army -- Materiel Command · Amount varies

The Army Applications Lab Broad Agency Announcement funds basic and applied scientific research in defense-relevant areas described in the BAA. Eligibility is unusually broad: institutions of higher education, nonprofits, state and local governments, foreign organizations and public entities, and for-profit businesses (large and small) may all apply. No specific award amount is listed, and projects are selected through full and open competition, so applicants should review the BAA's stated research areas of interest.

National Institute of Standards and Technology · From $10M

This NIST CHIPS R&D Office Broad Agency Announcement funds research, prototyping, and commercial solutions that advance U.S. microelectronics technology, with a stated floor of about $10 million per award. Eligible applicants include for-profit and non-profit organizations, accredited universities, FFRDCs, and federal entities, but they must be domestic; individuals and unincorporated sole proprietors are not eligible. Some foreign partners may participate as subawardees, subject to restrictions (foreign adversaries excluded). Given the large award size, applicants should review the full BAA for compliance requirements.

Munitions Directorate · Up to $750M

This Air Force (Munitions Directorate) Broad Agency Announcement funds research and development supporting air dominance, with a program ceiling reported up to roughly $750 million. Eligibility is described as unrestricted and open to any type of entity, subject to any clarifications in the full announcement, making it broadly accessible to businesses, universities, and nonprofits. Because it is defense-focused R&D, applicants should expect security and compliance requirements and should review the full BAA for specifics.

State Water Resources Control Board · $1–$15M

This program is open to California local public agencies, 501(c)(3) nonprofits, public utilities, state-recognized Native American tribes, and mutual water companies. The State Water Resources Control Board funds construction (and, for large-scale projects, planning and design) of recycled water treatment, storage, distribution, groundwater recharge, and related water-reuse infrastructure, with awards ranging from $1 up to $15 million. Operation and maintenance costs are not eligible, but all community types, including non-disadvantaged and disadvantaged, may apply. The application deadline is July 1, 2027.

Off of Temp & Disability Assi · Up to $30M

New York's Venture VI Program for SNAP Participants, run by the Office of Temporary and Disability Assistance, funds governmental entities and not-for-profit organizations to provide work-focused education and training services to low-income New Yorkers receiving SNAP benefits, with awards up to $30,000,000. The program reimburses only half of eligible contract payments with SNAP Employment & Training funds, meaning applicants must contribute matching non-federal resources for the rest. The deadline is July 22, 2030.

Centers for Disease Control and Prevention - ERA · Amount varies

This CDC health research opportunity (RFA-IP-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. The entry is a placeholder for Type 6 (continuation/competing renewal) applications and does not state award amounts or program specifics. Because it appears aimed at existing grantees, check with CDC about eligibility if you have not held a prior award.