National Institutes of Health Grants
654 open grant opportunities from National Institutes of Health, from Grants.gov — each with a plain-English summary of who qualifies, the deadline, and the award size.
Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)
Due Sep 25, 2028National Institutes of Health · Amount varies
Open to U.S. and foreign research institutions, universities, nonprofits, and certain government/tribal organizations. This NIH DP1 (Avant-Garde/Avenir) funds high-risk, high-reward research on HIV and substance use — basic, clinical, translational, or implementation science. It backs bold, transformative ideas; award size follows the DP1 mechanism.
ResearchersSchools & universitiesNonprofitsGovernment / tribalCancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
Due Sep 25, 2028National Institutes of Health · Amount varies
This NIH/NCI P30 Cancer Center Support Grant funds NCI-designated Cancer Centers to integrate their cancer research into a coordinated enterprise. Eligibility is highly restrictive: applicant institutions must already have a large cancer-focused NIH funding base (for example, $6M or $10M in annual direct costs depending on center type). Foreign organizations, foreign components of U.S. organizations, and foreign components are not eligible or allowed.
Schools & universitiesResearchersNarrow eligibilityAnimal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
Due Sep 26, 2028National Institutes of Health · Amount varies
This NIH/ORIP P40 grant funds Animal and Biological Material Resource Centers that maintain specialized animal colonies, cell and tissue cultures, genetic stocks, and related services for the biomedical research community. Proposed centers must have broad relevance across multiple NIH Institutes. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, and foreign components are not allowed.
ResearchersSchools & universitiesNarrow eligibilityResource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
Due Sep 28, 2028National Institutes of Health · Amount varies
This NIH/ORIP R24 grant funds research organizations to develop, characterize, or improve models of human health and disease (including new approach methodologies) that are broadly useful across two or more NIH Institutes. Projects narrowly tied to a single disease or to one Institute's interests will not be accepted. Foreign organizations, foreign components of U.S. organizations, and foreign components are not eligible or allowed.
ResearchersSchools & universitiesNarrow eligibilityBRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)
Due Oct 6, 2028National Institutes of Health · Amount varies
This NIH BRAIN Initiative U24 grant funds organizations to disseminate and integrate existing neuroscience research resources (tools, reagents, training, and access to platforms) into the broader research community. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, and applications involving funded foreign subawards/subcontracts will be rejected. Applicants are typically established research institutions with an existing resource to share.
ResearchersSchools & universitiesNarrow eligibilityUsing Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)
Due Oct 20, 2028National Institutes of Health · Up to $200K
This NIH R21 grant funds secondary analyses that use archived HIV/AIDS data sets and specimen collections to answer questions about maternal, pediatric, and adolescent HIV/AIDS. Both U.S. and foreign organizations are eligible to apply, but foreign components within a project are not allowed. The award ceiling is up to about $200,000.
ResearchersSchools & universitiesBroad eligibilitySingle-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)
Due Nov 2, 2028National Institutes of Health · Amount varies
This NIH/NHLBI R61/R33 cooperative agreement funds investigator-initiated single-site clinical trials relevant to the NHLBI mission, using a milestone-driven, two-phase structure. Both U.S. and foreign organizations may apply, but applications including funded foreign subawards/subcontracts will be deemed noncompliant. Applicants are encouraged to include expertise in biostatistics and clinical trial design.
ResearchersSchools & universitiesBroad eligibilityData Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
Due Nov 2, 2028National Institutes of Health · Amount varies
This NIH/NHLBI U24 cooperative agreement funds a Data Coordinating Center to provide data management, biostatistics, and project coordination for investigator-initiated multi-site clinical trials. A companion Clinical Coordinating Center application must be submitted on the same due date for consideration. Both U.S. and foreign organizations may apply, but applications with funded foreign subawards/subcontracts will be rejected.
ResearchersSchools & universitiesBroad eligibilityClinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Due Nov 2, 2028National Institutes of Health · Amount varies
This NIH/NHLBI UG3/UH3 cooperative agreement funds a Clinical Coordinating Center to lead and operate investigator-initiated multi-site clinical trials relevant to the NHLBI mission. A companion Data Coordinating Center application must be submitted on the same due date. Both U.S. and foreign organizations may apply, but applications with funded foreign subawards/subcontracts will be rejected.
ResearchersSchools & universitiesBroad eligibilityCCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)
Due Nov 5, 2028National Institutes of Health · Up to $300K
This NIH R01 grant funds basic research into how toxic chemicals of concern injure the skin, supporting the development of medical countermeasures for chemical disasters and emergencies. The award ceiling is up to about $300,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.
ResearchersSchools & universitiesNarrow eligibilityEarly Immune System Development and Ontogeny (R01 Clinical Trial Optional)
Due Nov 5, 2028National Institutes of Health · Up to $400K
This NIH R01 grant funds research into early immune system development from the prenatal period through early childhood, including effects of in-utero HIV or antiretroviral exposure. A broad range of applicants is eligible, including colleges and universities, tribal governments, faith- and community-based organizations, minority-serving institutions, and foreign organizations. The award ceiling is up to about $400,000.
ResearchersSchools & universitiesNonprofitsGovernment / tribal+1 moreLimited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
Due Nov 7, 2028National Institutes of Health · Up to $85K
This NIH/NHLBI R03 small grant is a limited competition open only to current or recently completed NHLBI K01, K08, K23, and K25 career-development awardees, to help them transition toward independent research. Projects must be completable in two years, and applicants must maintain at least 40% protected research effort. The award ceiling is up to about $85,000, and foreign organizations are not eligible to apply.
ResearchersSchools & universitiesNarrow eligibilitySmall awardCommunity-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)
Due Nov 16, 2028National Institutes of Health · Up to $300K
This NIH UG3/UH3 cooperative agreement funds community-based participatory research that tests population-level interventions to improve oral health by addressing social and chronic-disease risk factors through cross-sector community partnerships. The award ceiling is up to about $300,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, and foreign components are not allowed.
ResearchersSchools & universitiesNonprofitsNarrow eligibilityThe Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Due Nov 22, 2028National Institutes of Health · Up to $500K
This NIH/NCI U01 cooperative agreement funds research projects within the Metastasis Research Network that use systems-level approaches to study cancer metastasis as a whole-body problem. Both U.S. and foreign organizations may apply, but applications including funded foreign subawards/subcontracts will be deemed noncompliant. The award ceiling is up to about $500,000.
ResearchersSchools & universitiesLarge awardBroad eligibilityAdministrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Due Nov 30, 2028National Institutes of Health · Amount varies
This NIH opportunity provides administrative supplements only to organizations that already hold an active, eligible NIH grant or cooperative agreement, to cover unforeseen increased costs within the scope of the existing project. New applicants without a current NIH award cannot use it. Funding is not guaranteed, and applicants must discuss requests with the awarding Institute's staff before submitting; foreign organizations may apply only consistent with the existing parent award.
ResearchersSchools & universitiesNarrow eligibilityLimited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
Due Jan 26, 2029National Institutes of Health · $25K–$250K
This NIH S10 instrumentation grant funds resource-limited institutions to purchase state-of-the-art scientific instruments supporting biomedical research and education. It is a limited competition that invites applications only from eligible organizations, and awards range from about $25,000 to $250,000. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.
Schools & universitiesResearchersNarrow eligibilityBiomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)
Due Jan 29, 2029National Institutes of Health · Amount varies
This NIH/NIGMS RM1 grant funds Biomedical Technology Optimization and Dissemination Centers to refine late-stage research technologies and sustainably share them with the wider biomedical research community. Applicants should be leaders in their technology field and within the NIGMS mission. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.
ResearchersSchools & universitiesNarrow eligibilityMaximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)
Due Feb 6, 2029National Institutes of Health · Amount varies
This NIH/NIGMS award (MIRA for Early Stage Investigators) funds early-career biomedical researchers at U.S. institutions to run an independent research program aligned with the NIGMS mission. It is aimed at Early Stage Investigators, so it is restrictive by career stage. Non-U.S. (foreign) institutions and foreign components of U.S. organizations are not eligible to apply, though foreign components within projects may be allowed per NIH policy.
ResearchersSchools & universitiesNarrow eligibilityHEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
Due Feb 9, 2029National Institutes of Health · Amount varies
This NIH HEAL Initiative R61/R33 grant funds action-oriented research that translates addiction epidemiology, prevention, treatment, and recovery findings into practice to address the opioid crisis and overdose. Projects can target individual, provider, organizational, community, or system levels. Foreign organizations and foreign components of U.S. organizations are not eligible to apply, though foreign components within a project may be allowed.
ResearchersSchools & universitiesNarrow eligibilityHEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
Due Feb 20, 2029National Institutes of Health · Amount varies
This NIH HEAL Initiative UG3/UH3 cooperative agreement funds preclinical optimization and development of safe, non-addictive small-molecule and biologic therapeutics for treating pain, advancing candidates toward Phase II trials. Applicants must already have a promising lead candidate, a strong biological rationale, and established assays. Foreign organizations and foreign components of U.S. organizations are not eligible to apply.
ResearchersSmall businessSchools & universitiesNarrow eligibility
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How many National Institutes of Health grants are open right now?
UseGrants is tracking 654 open National Institutes of Health opportunities. The next one closes Sep 25, 2028. The largest published award ceiling on this page is $500,000. The list is rebuilt from public records daily, so an opportunity drops off it the day its deadline passes.
Who can apply for National Institutes of Health funding?
Eligibility is set per opportunity, not per agency — the same funder will run one program open to any nonprofit and another restricted to accredited universities. Across the National Institutes of Health opportunities listed here the recurring eligibility signals are researchers, schools & universities, nonprofits and government / tribal. Every listing still states its own terms in plain English; confirm them on the funder's official notice before you apply.