Grants for Researchers

National Institutes of Health · Amount varies

This NIH/NIAID (U01) cooperative agreement funds the implementation of investigator-initiated, milestone-driven clinical trials that need enhanced oversight, optionally including mechanistic studies, for up to 5 (or extended 6-7) years. A clinical trial is required and only one trial may be proposed per application, so it suits research institutions ready to run a defined trial in infectious disease or immunology. Eligibility is comparatively open for NIH: foreign organizations and foreign components of U.S. organizations are both eligible to apply, and foreign components are allowed.

National Institutes of Health · Up to $500K

This NIH/NIDCR (U01) cooperative agreement funds investigator-initiated observational or biomarker validation studies that require prospective collection or continued analysis of data and biospecimens, with a stated budget up to about $500,000. It is aimed at research institutions in NIDCR (dental, oral, and craniofacial) mission areas. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.

National Institutes of Health · Amount varies

This NIH/NCI (U01) cooperative agreement funds research using cancer epidemiology cohort studies to address gaps in cancer causes and survivorship, including cohort infrastructure, continued follow-up, and data/biospecimen sharing. It is aimed at research institutions running or analyzing large epidemiologic cohorts. Eligibility is comparatively open for NIH: foreign organizations and foreign components of U.S. organizations are eligible to apply, though foreign components as defined by NIH are not allowed. Clinical trials are not permitted under this NOFO.

National Institutes of Health · Up to $500K

This NIH (U01) cooperative agreement funds research into the human behaviors that affect oral and systemic health among people with chronic conditions, including projects that develop or test causal hypotheses, with a stated budget up to about $500,000. It is aimed at research institutions studying behavioral, biological, and psychosocial drivers of health outcomes. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.

National Institutes of Health · Amount varies

This NIH career development award (K32) supports up to three years of mentored research and career development for early-stage postdoctoral scholars, with applications submitted around the start of the postdoctoral position. It is an institutional/mentored mechanism aimed at developing future independent investigators, so it suits universities and research institutions. Only domestic U.S. organizations may apply; foreign organizations are not eligible, though foreign components are allowed.

National Institutes of Health · Amount varies

This NIH/NIAMS Small Grant (R03) is a limited competition restricted to existing recipients of certain mentored career development awards (K01, K08, K23, K25 or comparable federal/non-federal awards) in NIAMS mission areas. It provides up to $50,000 in direct costs per year for up to two years to support short, self-contained projects that help researchers transition to independence. Eligibility is narrow and by invitation, and only domestic U.S. organizations may apply; foreign organizations are not eligible. Clinical trials are not allowed.

Air Force -- Research Lab · $0–$49M

This Air Force Research Laboratory funding opportunity supports university research and development in directed energy, with a program cost ceiling of roughly $49 million and a mandatory letter of intent required before full proposals. The announcement is aimed at universities (university assistance instruments), but full eligibility details are in the FOA itself, which applicants must consult. Because it is defense-focused, expect a security risk review as part of the selection process.

Air Force -- Research Lab · Up to $99M

This Air Force Research Laboratory opportunity funds research in automated knowledge discovery and information retrieval, with a ceiling reported up to roughly $99 million across the program. Note that no Grants.gov submissions are accepted; all applications must follow instructions in the linked SAM.gov announcement, which also contains the full eligibility details. Because the eligibility criteria are not stated here, prospective applicants must review the SAM.gov notice to confirm whether they qualify.

Advanced Research Projects Agency Energy · $5M–$20M

ARPA-E's SCALEUP READY program funds the scale-up of promising clean and advanced energy technologies, with awards in the range of roughly $5 million to $20 million. It targets organizations developing transformative energy technologies aimed at improving U.S. energy security, efficiency, and emissions. Specific eligibility is set out in the NOFO (Section II.A.) available on the ARPA-E eXCHANGE site; applications must be submitted through that portal rather than Grants.gov, and cost-share is typical for ARPA-E awards, so review the NOFO before applying.

National Institute of Standards and Technology · From $10M

This NIST CHIPS R&D Office Broad Agency Announcement funds research, prototyping, and commercial solutions that advance U.S. microelectronics technology, with a stated floor of about $10 million per award. Eligible applicants include for-profit and non-profit organizations, accredited universities, FFRDCs, and federal entities, but they must be domestic; individuals and unincorporated sole proprietors are not eligible. Some foreign partners may participate as subawardees, subject to restrictions (foreign adversaries excluded). Given the large award size, applicants should review the full BAA for compliance requirements.

Munitions Directorate · Up to $750M

This Air Force (Munitions Directorate) Broad Agency Announcement funds research and development supporting air dominance, with a program ceiling reported up to roughly $750 million. Eligibility is described as unrestricted and open to any type of entity, subject to any clarifications in the full announcement, making it broadly accessible to businesses, universities, and nonprofits. Because it is defense-focused R&D, applicants should expect security and compliance requirements and should review the full BAA for specifics.

Naval Supply Systems Command · $0

This Naval Postgraduate School opportunity funds basic and applied STEM research (not hardware procurement or development of a specific system). Eligible applicants are public and private institutions of higher education and 501(c)(3) nonprofits other than universities, so it is restricted to academic and nonprofit research organizations. Applicants are encouraged to first submit a white paper to NPS for feedback before submitting a full proposal through Grants.gov. No award amount is specified.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-CK-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. It is listed only as a placeholder for Type 6 (continuation/competing renewal) applications, with no award amounts or specific requirements provided. Because it appears intended for existing grantees, confirm with CDC whether new applicants can apply.

Centers for Disease Control and Prevention - ERA · $0

This is a CDC health research opportunity (RFA-CE-18-000) open to a broad range of applicants, including states, universities, counties, small businesses, and nonprofit organizations. It is described only as a placeholder for Type 6 (continuation/competing renewal) applications, so funding amounts and specific program details are not stated. Because it appears geared toward existing grantees submitting renewal-type applications, confirm with CDC whether new applicants are eligible before applying.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-CC-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. The listing is a placeholder for Type 6 (continuation/competing renewal) applications and gives no award amounts or program details. As it appears geared toward existing grantees, verify with CDC whether new organizations can apply.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-TS-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. The listing is a placeholder for Type 6 (continuation/competing renewal) applications and does not state award amounts or detailed program requirements. Since it appears aimed at existing grantees filing renewal-type applications, verify eligibility with CDC if you are a first-time applicant.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-PS-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. The listing is a placeholder for Type 6 (continuation/competing renewal) applications and provides no award amounts or specific program details. Since it appears intended for existing grantees, verify with CDC whether new applicants are eligible.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-IP-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. The entry is a placeholder for Type 6 (continuation/competing renewal) applications and does not state award amounts or program specifics. Because it appears aimed at existing grantees, check with CDC about eligibility if you have not held a prior award.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-OE-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. It is listed only as a placeholder for Type 6 (continuation/competing renewal) applications, with no award amounts or detailed requirements. Since it appears intended for existing grantees, confirm eligibility with CDC before applying as a new applicant.

Centers for Disease Control and Prevention - ERA · $0

This CDC health research opportunity (RFA-CD-18-000) is open to states, universities, counties, small businesses, and nonprofit organizations. It is a placeholder for Type 6 (continuation/competing renewal) applications, with no stated award amounts or specific requirements. Because it appears aimed at existing grantees, confirm eligibility with CDC if you are a first-time applicant.