Grants for Nonprofits

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial not allowed) supporting screening and functional validation of genomic variants linked to human congenital anomalies, developmental disabilities, and inborn errors of metabolism. A broad set of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a basic-science genomics mechanism for research institutions.

National Institutes of Health · Amount varies

A limited-competition NIH planning grant (R34, clinical trial not allowed) supporting fundamental research on skin injuries caused by chemical threats and potential shared therapeutic targets. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations and foreign components of U.S. organizations are not eligible, though foreign components within the project are allowed. No specific award amount is stated. As a limited competition, eligibility may be further restricted beyond the listed categories, so review the NOFO closely.

National Institutes of Health · Amount varies

An NIH/NCI exploratory grant (R21, clinical trial not allowed) funding proof-of-concept studies on the mechanisms by which bariatric surgery affects cancer risk. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. Projects must address feasibility not already established in the literature, so this suits research institutions with relevant preliminary direction.

National Institutes of Health · Up to $75K

A limited-competition NIH/NIDDK Small Grant (R03) available only to existing NIDDK-supported K01, K08, K23, and K25 career-award recipients, to support their transition to independent investigator status. A broad set of domestic and foreign institutions may apply on their behalf, but the underlying applicant must already hold a qualifying NIDDK K award. The grant is capped at about $75,000. This is restricted to current NIDDK career-award holders, not new applicants.

National Institutes of Health · Amount varies

An NIH/NCI exploratory/developmental bioengineering research grant (EBRG, R21, clinical trial optional) funding feasibility-stage projects that develop new capabilities or improvements for biomedical, pre-clinical, or clinical research and care. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a bioengineering research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

An NIH/NIDCD dissertation fellowship (F32) supporting Au.D. audiologists pursuing rigorous biomedical research training and dissertation research toward a research doctorate. A broad range of domestic and foreign institutions may apply as the sponsoring organization, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an individual fellowship mechanism administered through a sponsoring institution, aimed at audiologist trainees.

National Institutes of Health · Amount varies

An NIH/NCI exploratory/developmental bioengineering research grant (EBRG, R21, clinical trial not allowed) funding feasibility-stage projects that develop new capabilities or improvements for biomedical, pre-clinical, or clinical research and care. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a bioengineering research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial required) supports investigator-initiated research projects, with at least one clinical trial required, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Up to $499K

An NIH/NCI research project grant (R01, clinical trial not allowed) funding academic-industrial partnerships to translate scientific and engineering advances into tools for disease risk assessment, detection, diagnosis, and treatment. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. The award is capped at about $499,000. The partnership focus suits research institutions collaborating with industry rather than individuals.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trials optional) supporting population-based research on how work and occupation influence health outcomes among populations with health disparities. Eligible applicants are domestic institutions such as universities, tribal governments, and community-based organizations; foreign organizations, foreign components of U.S. organizations, and foreign components are not eligible. No specific award amount is stated. This suits research institutions conducting population health-disparities research.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial not allowed) supports early-stage, higher-risk research projects that may lead to breakthroughs or novel methods. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is an exploratory research mechanism aimed at research institutions.

National Institutes of Health · Amount varies

The NIH parent Exploratory/Developmental Research Grant (R21, clinical trial required) supports early-stage research projects with at least one clinical trial, aligned with participating NIH institutes' missions. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. The clinical-trial requirement makes this best suited to research institutions with trial capacity.

National Institutes of Health · Amount varies

An NIH research project grant (R01, clinical trial not allowed) funding development of next-generation neuromodulation and neurostimulation devices for treating mental health disorders. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. Incremental updates to existing devices are out of scope, so this suits research institutions developing novel device technology.

National Institutes of Health · Amount varies

Open to a broad range of research organizations including universities, minority-serving institutions, tribal governments, faith- and community-based organizations, and foreign organizations under this NIH R01 mechanism (clinical trial optional). Funds studies that test strategies for adopting, scaling up, sustaining, or de-implementing evidence-based health interventions and policies, including services disrupted by disasters such as pandemics. Work must fall within the mission of a participating NIH Institute or Center; no specific award ceiling is stated.

National Institutes of Health · Amount varies

Open to a broad range of research organizations including universities, minority-serving institutions, tribal governments, faith- and community-based organizations, and foreign organizations under this NIH R21 exploratory mechanism (clinical trial optional). Funds studies developing and testing strategies to adopt, scale up, sustain, or de-implement evidence-based health interventions, practices, and policies, and to advance dissemination/implementation research methods. Work must align with a participating NIH Institute or Center; no specific award amount is listed.

National Institutes of Health · Amount varies

Open to domestic research organizations including universities, minority-serving institutions, tribal governments, and faith- and community-based groups under this NIGMS R01; foreign organizations and foreign components are not eligible. Funds development of new technologies that enable acquisition of biomedical knowledge, with a focus on technical innovation that can advance the state of the art across a broad range of biomedical research. No clinical trial is allowed and no specific award amount is stated.

National Institutes of Health · Amount varies

Open to a broad range of U.S. research organizations including universities, minority-serving institutions, tribal governments, and faith- and community-based groups under this NICHD R01 (clinical trial optional). Funds studies expanding knowledge of the natural history of disorders that are or may become part of statewide newborn screening programs, to inform diagnosis, treatment, and clinical trials. No specific award amount is listed.

National Institutes of Health · Amount varies

The NIH parent Research Project Grant (R01, clinical trial not allowed) supports investigator-initiated research projects aligned with participating NIH institutes' missions, excluding clinical trials. A broad range of domestic and foreign institutions may apply, including universities, tribal governments, and community-based organizations. No specific award amount is stated. This is a core NIH research mechanism aimed at research institutions.

Washington Headquarters Services · $0–$100M

A Department of War (Washington Headquarters Services) non-research cooperative agreement program to help manage and sustain DoW land in the U.S. through natural and cultural resource projects supporting installation resilience and military readiness. Eligibility is very broad: public and private agencies, organizations, institutions, and individuals are invited to apply. Awards range widely, up to about $100 million. The broad eligibility, including individuals, is unusual, so confirm specific requirements in the announcement.

National Institutes of Health · Amount varies

An NIH (R38) award supporting in-depth research experiences for resident clinicians early in their careers to build a pipeline of clinician-investigators. Eligible applicants are domestic institutions and organizations such as universities, tribal governments, and faith- or community-based organizations; foreign organizations and foreign components are not eligible. No award amount is stated. This is a structured research-training mechanism aimed at academic and clinical institutions rather than individuals applying directly.