Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
This NIH Gabriella Miller Kids First X01 supports submitting pediatric cohort samples for whole genome and related sequencing to study the genetic basis of childhood cancers and congenital anomalie…
- Deadline
- Jan 11, 2027
- Posted
- Jun 18, 2026
- Award amount
- Amount not specified
- Focus areas
- Health
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In plain English
This NIH Gabriella Miller Kids First X01 supports submitting pediatric cohort samples for whole genome and related sequencing to study the genetic basis of childhood cancers and congenital anomalies; no clinical trial is allowed. Foreign (non-U.S.) organizations and foreign components are not eligible. This award provides sequencing at supported genomic centers rather than a cash research budget, so applicants should review the notice; no specific award amount is stated. It is aimed at research teams with existing pediatric cohorts.
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Who can apply
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
About this grant
As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program supported genomic data generating centers. Applicants are encouraged to propose sequencing of existing pediatric cancer or congenital anomaly cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of congenital anomalies, to study the molecular basis of the associations between congenital anomalies and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as clinical-grade sequencing, long-read sequencing, proteomics, and epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts to increase representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.
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