Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)
This NIH (U01) cooperative agreement funds research into the human behaviors that affect oral and systemic health among people with chronic conditions, including projects that develop or test causa…
- Deadline
- Jul 5, 2029
- Posted
- Jun 4, 2026
- Award amount
- Up to $500,000
- Focus areas
- Health
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We’ll email you before Jul 5, 2029 so you have time to apply.
In plain English
This NIH (U01) cooperative agreement funds research into the human behaviors that affect oral and systemic health among people with chronic conditions, including projects that develop or test causal hypotheses, with a stated budget up to about $500,000. It is aimed at research institutions studying behavioral, biological, and psychosocial drivers of health outcomes. Only domestic U.S. organizations may apply; foreign organizations are not eligible and foreign components are not allowed. Clinical trials are not permitted under this NOFO.
AI-generated summary to help you decide quickly — verify the official eligibility rules before applying.
Who can apply
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
About this grant
This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal hypotheses may include biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, and comorbidity factors that individually, sequentially, or in combination trigger human behaviors and oral-systemic health outcomes, with impacts that may be direct or traceably distal. Applications that propose projects to develop or refine causal hypotheses also are encouraged.
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