Health Grants

National Institutes of Health · Up to $500K

An NIH UC2 program helping resource-limited organizations build biomedical research capacity and sponsored-programs administration. Eligible applicants include minority-serving and Tribal colleges and other domestic organizations with limited research resources; foreign organizations are not eligible. Awards reach up to about $500,000. This targets emerging or under-resourced research institutions rather than general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $1M

An NIH/NIDDK P30 center grant funding shared research cores and a pilot/feasibility program for diabetes and related metabolic disease research. It is aimed at institutions with an established diabetes research base; only one application per institution is allowed, and foreign organizations are not eligible. Awards reach up to about $1,000,000. This is a center-scale research award for established institutions, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage investigators to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent small clinical study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This NOFO is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress.

National Institutes of Health · Up to $750K

An NIH BRAIN Initiative R18 funding preclinical proof-of-concept work on novel recording and modulation technologies for the human central nervous system, up to readiness for first-in-human studies. The eligibility text is mixed but states foreign organizations and foreign components are not eligible to apply, while domestic research institutions, minority-serving and Tribal colleges may. Awards reach up to about $750,000, and clinical trials are not allowed. This is a specialized research award, not a fit for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH BRAIN Initiative R01 funding the development and validation of novel tools to study cell-type- and circuit-specific processes in the brain. Eligibility is geared toward research institutions, including HBCUs, Hispanic-serving and Tribal colleges, and foreign organizations; this is a federal research grant, not a fit for typical nonprofits, small businesses, or individuals without an academic/research affiliation. No award amount is specified. Clinical trials are not allowed under this opportunity.

National Institutes of Health · Up to $750K

An NIH P30 center grant funding shared research cores for digestive and liver diseases research. Only institutions with a strong existing research base, including at least $3 million per year in relevant direct-cost funding (with at least 30% from NIDDK), are eligible, so this effectively requires being an established, heavily NIH-funded institution. Foreign organizations are not eligible. Awards reach up to about $750,000. This is a narrow opportunity for major research centers, not for typical nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $700K

An NIH BRAIN Initiative R61 funding exploratory human neuroscience using invasive neural recording and stimulation during surgical procedures. Foreign organizations and foreign components are not eligible; the work requires multidisciplinary teams with access to neurosurgical settings. Awards reach up to about $700,000, and clinical trials are not allowed. This is a highly specialized research award for institutions with relevant clinical/research capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIDA U01 cooperative agreement funding animal-genomics research into variants linked to addiction and substance use disorders. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified, and clinical trials are not allowed. This is a federal research grant aimed at investigators, not general nonprofits, small businesses, or individuals.

Centers for Disease Control - OPHPR · $50K–$5M

A CDC cooperative agreement that pre-positions states, large local governments, and federally recognized Tribes on an approved-but-unfunded roster for rapid public-health emergency response. Eligibility is limited to government public-health entities, with population thresholds (e.g., counties of 2 million or more, cities of 400,000 or more, Tribes serving 50,000 or more), so it is restricted to large jurisdictions. Listed award range is about $50,000 to $5,000,000, but funding is only released if a public health emergency is declared. Not a fit for nonprofits, small businesses, individuals, or smaller jurisdictions.

Bureau of Global Health Security and Diplomacy · $500K–$250M

A State Department Annual Program Statement supporting projects that advance U.S. global health priorities under bilateral agreements. Eligibility is defined by the separate APS instructions and is not detailed here, so requirements are vague and applicants should review the APS before assuming they qualify. The stated award range is very wide, from roughly $500,000 up to $250,000,000. Because eligibility is unspecified and tied to State Department priorities, fit is uncertain for general nonprofits.

National Institutes of Health · Amount varies

An NIH/NHGRI R01 supporting early-stage investigators pursuing genomics research, across genomic sciences, medicine, data science, and ethical/legal/social implications. Foreign organizations are not eligible; domestic research institutions, minority-serving and Tribal colleges may apply, and the program targets researchers in an early-career stage. No award amount is specified. This is a research grant for academic/early-career investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH X01 award giving researchers access to stored All of Us biospecimens (plasma, serum, DNA) to run assays and add data back to the program. It is aimed at scientific investigators, including foreign organizations, who can conduct multiomics and biomarker analyses; it is a resource-access award rather than a general grant. No dollar amount is specified, and clinical trials are not allowed. Not a fit for nonprofits, small businesses, or individuals outside the research community.

National Institutes of Health · Amount varies

An NIH/NIAMS UG3/UH3 cooperative agreement funding the implementation of clinical trials, where a clinical trial is required. The eligibility text is internally mixed but states that foreign organizations and foreign components of U.S. organizations are not eligible to apply, while domestic research institutions, minority-serving and Tribal colleges may apply. No award amount is specified. This is a clinical-research award for institutions equipped to run trials, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $1.5M

An NIH RM1 funding team-based research at the intersection of HIV and substance use, requiring a detailed research plan and preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges; foreign organizations and foreign components are not eligible to apply. Awards reach up to about $1,500,000. This is a research-team grant for established investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R01 funding discovery and optimization of in vivo chemical probes for novel nervous-system targets, with applicants expected to already have validated starting compounds and bioassays in hand. Domestic and foreign organizations and foreign components are eligible to apply. No award amount is specified, and clinical trials are not allowed. This is a research grant for investigators with existing medicinal-chemistry capacity, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R01 funding innovative research at the intersection of HIV and substance use, open to both individual investigators and research teams, and requiring a detailed research plan with preliminary data. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is a research grant for investigators, not for general nonprofits, small businesses, or individuals without a research affiliation.

National Institutes of Health · Up to $500K

An NIH U01 supporting collaborative translational research conducted with NIH intramural investigators using the NIH Clinical Center. Domestic and foreign organizations may apply, but NIH will not fund awards involving foreign subawards/subcontracts under this opportunity, so applications relying on foreign subawards are excluded. Awards reach up to about $500,000. This is a research grant for investigators able to partner with NIH, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Up to $500K

An NIH/NIDDK U01 continuing the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) consortium to study cardiovascular disease in people with type 1 diabetes. Foreign organizations and foreign components are not eligible to apply, and clinical trials are not allowed; it is tied to the existing consortium effort. Awards reach up to about $500,000. This is a specialized research-consortium award for investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

An NIH R34 funding formative research and pilot-testing of behavioral, social, structural, or combination interventions to improve HIV prevention and treatment for people who use drugs; a clinical trial is required. Eligible applicants include research institutions, minority-serving and Tribal colleges, and foreign organizations. No award amount is specified. This is an early-stage clinical-research grant for investigators, not for general nonprofits, small businesses, or individuals.

National Institutes of Health · Amount varies

This NIH/CDC/FDA SBIR program (R43/R44) funds U.S. small businesses developing scientific innovations toward commercial products through feasibility and R&D studies. Eligibility is limited to U.S. small business concerns as defined by the SBA, and foreign organizations are not eligible. No award amount is listed.